Human geneticist at MSK. Prev. postdoc at Stanford and BS + PhD at Cornell. avid skier, runner, and Yankee fan.https://bsky.app/profile/amarderstein.bsky.socialhttps://bsky.app/profile/amarderstein.bsky.social/post/3mtkqtoc3jk2eExcited and honored to have been elected last week to the ASHG Board of Directors! @geneticssociety.bsky.social I’m excited to continue to support the next generation of geneticists, and help shape the future of human genetics. Thank you to everyone who supported me.21 Aug 2026 02:50 +0000at://did:plc:ovo5bvc3y2zhx37o7vpf727f/app.bsky.feed.post/3mtkqtoc3jk2ehttps://bsky.app/profile/amarderstein.bsky.social/post/3mp76oj4azk2t@sbmontgom.bsky.social and I wrote a Research Briefing on our recent Nature Genetics paper! We summarize the study, along with some behind-the-scenes thoughts on how the project came together and what we learned along the way. https://www.nature.com/articles/s41588-026-02618-7 [contains quote post or other embedded content]26 Jun 2026 14:45 +0000at://did:plc:ovo5bvc3y2zhx37o7vpf727f/app.bsky.feed.post/3mp76oj4azk2thttps://bsky.app/profile/amarderstein.bsky.social/post/3modlrlljh22mOur latest is out in Nature Genetics with @soumyakundu.bsky.social @anshulkundaje.bsky.social and @sbmontgom.bsky.social ! We built a resource of predicted variant effects on chromatin accessibility, and FLARE to identify disease variants with extreme effects. https://www.nature.com/articles/s41588-026-02619-615 Jun 2026 15:25 +0000at://did:plc:ovo5bvc3y2zhx37o7vpf727f/app.bsky.feed.post/3modlrlljh22mhttps://bsky.app/profile/amarderstein.bsky.social/post/3lijv7rd4bc27New preprint w/ @soumyakundu.bsky.social @sbmontgom.bsky.social @anshulkundaje.bsky.social ! Using deep learning & scATAC-seq, we studied context-specific variants in disease & evolution, and introduce FLARE for de novo mutations—w/ application to autism-affected families. https://doi.org/10.1101/2025.02.18.638922 https://www.biorxiv.org/content/10.1101/2025.02.18.638922v119 Feb 2025 13:32 +0000at://did:plc:ovo5bvc3y2zhx37o7vpf727f/app.bsky.feed.post/3lijv7rd4bc27https://bsky.app/profile/amarderstein.bsky.social/post/3lhjsunuob226Submissions for ASHG 2025’s Featured Symposium are due Feb 10 at 5:00 pm ET! Let me know if you have any questions. We're excited to see a wide range of proposals, ranging from AI/ML applications, clinical genetics, women's health, and more. https://www.ashg.org/meetings/2025meeting/present/featured-symposia/06 Feb 2025 19:25 +0000at://did:plc:ovo5bvc3y2zhx37o7vpf727f/app.bsky.feed.post/3lhjsunuob226https://bsky.app/profile/amarderstein.bsky.social/post/3lfsfaht2kc2uMarker paper of the new dGTEx consortium is now published, describing the development of a new reference dataset for genomics research across human and non-human development! https://www.nature.com/articles/s41586-024-08244-9#Abs115 Jan 2025 18:25 +0000at://did:plc:ovo5bvc3y2zhx37o7vpf727f/app.bsky.feed.post/3lfsfaht2kc2uhttps://bsky.app/profile/amarderstein.bsky.social/post/3lcdlkhtzfc2t“our analyses suggest that less than 1% of blastocysts are fully euploid, and that many embryos possess low-level mosaic clones that are not captured during biopsy” [contains quote post or other embedded content]02 Dec 2024 16:52 +0000at://did:plc:ovo5bvc3y2zhx37o7vpf727f/app.bsky.feed.post/3lcdlkhtzfc2t