Research Assistant Professor with Gemma Carvill (@CarvillLab on Twitter). Focus: epilepsy genetics. Twin. Ace cat dad. Occasional writer. I am only an egg. He/him.https://bsky.app/profile/calhoujd.bsky.socialhttps://bsky.app/profile/calhoujd.bsky.social/post/3mqeuxmphvs2hOur paper on integrating data from 2+ multiplexed assays of variant effect (MAVE) for the same gene is available now: https://doi.org/10.1186/s13073-026-01715-w We also have a Shiny webtool where you can plug in data and compare a few different integration approaches. A big thank you to all co-authors... 1/311 Jul 2026 14:32 +0000at://did:plc:oykhpsffhd33f5kv6kbaqlk2/app.bsky.feed.post/3mqeuxmphvs2hhttps://bsky.app/profile/calhoujd.bsky.social/post/3mqeuxmphvs2hOur paper on integrating data from 2+ multiplexed assays of variant effect (MAVE) for the same gene is available now: https://doi.org/10.1186/s13073-026-01715-w We also have a Shiny webtool where you can plug in data and compare a few different integration approaches. A big thank you to all co-authors... 1/311 Jul 2026 14:32 +0000at://did:plc:oykhpsffhd33f5kv6kbaqlk2/app.bsky.feed.post/3mqeuxmphvs2hhttps://bsky.app/profile/calhoujd.bsky.social/post/3mqa6geedys2vI am proud to share our paper using two complementary approaches to resolve variants of uncertain significance (VUS) in the gene TSC2. VUS are a barrier to achieving a precise genetic diagnosis for tuberous sclerosis complex and some cancers. 1/14 https://www.nature.com/articles/s41467-026-75442-609 Jul 2026 17:38 +0000at://did:plc:oykhpsffhd33f5kv6kbaqlk2/app.bsky.feed.post/3mqa6geedys2vhttps://bsky.app/profile/calhoujd.bsky.social/post/3mqa6geedys2vI am proud to share our paper using two complementary approaches to resolve variants of uncertain significance (VUS) in the gene TSC2. VUS are a barrier to achieving a precise genetic diagnosis for tuberous sclerosis complex and some cancers. 1/14 https://www.nature.com/articles/s41467-026-75442-609 Jul 2026 17:38 +0000at://did:plc:oykhpsffhd33f5kv6kbaqlk2/app.bsky.feed.post/3mqa6geedys2vhttps://bsky.app/profile/calhoujd.bsky.social/post/3md2gh4lw322lPet #2 [contains quote post or other embedded content]23 Jan 2026 00:18 +0000at://did:plc:oykhpsffhd33f5kv6kbaqlk2/app.bsky.feed.post/3md2gh4lw322lhttps://bsky.app/profile/calhoujd.bsky.social/post/3md2fxboad224Pet #1 [contains quote post or other embedded content]23 Jan 2026 00:10 +0000at://did:plc:oykhpsffhd33f5kv6kbaqlk2/app.bsky.feed.post/3md2fxboad224https://bsky.app/profile/calhoujd.bsky.social/post/3mcrta3crcc2aExcited to share our work to resolve TSC2 variants of uncertain significance. Will write a proper tweetorial soon! Huge thanks to our many collaborators. This study benefited from the hard work of many folks and I appreciate them lending their time and expertise. [contains quote post or other embedded content]19 Jan 2026 14:13 +0000at://did:plc:oykhpsffhd33f5kv6kbaqlk2/app.bsky.feed.post/3mcrta3crcc2ahttps://bsky.app/profile/calhoujd.bsky.social/post/3mcrta3crcc2aExcited to share our work to resolve TSC2 variants of uncertain significance. Will write a proper tweetorial soon! Huge thanks to our many collaborators. This study benefited from the hard work of many folks and I appreciate them lending their time and expertise. [contains quote post or other embedded content]19 Jan 2026 14:13 +0000at://did:plc:oykhpsffhd33f5kv6kbaqlk2/app.bsky.feed.post/3mcrta3crcc2ahttps://bsky.app/profile/calhoujd.bsky.social/post/3mbcwwxwv222mJarring homemade preserves just to seal something [contains quote post or other embedded content]31 Dec 2025 22:44 +0000at://did:plc:oykhpsffhd33f5kv6kbaqlk2/app.bsky.feed.post/3mbcwwxwv222mhttps://bsky.app/profile/calhoujd.bsky.social/post/3m2uxppz5vs23@coachnelly.bsky.social caught Oki Oki FC vod today. Awesome to see your progress, keep it up!11 Oct 2025 00:50 +0000at://did:plc:oykhpsffhd33f5kv6kbaqlk2/app.bsky.feed.post/3m2uxppz5vs23https://bsky.app/profile/calhoujd.bsky.social/post/3lwecvfc24s2pI don't work with fruit flies but even I know how important FlyBase is. Such sad news. 😞 [contains quote post or other embedded content]14 Aug 2025 12:14 +0000at://did:plc:oykhpsffhd33f5kv6kbaqlk2/app.bsky.feed.post/3lwecvfc24s2phttps://bsky.app/profile/calhoujd.bsky.social/post/3lqp7se634s2q@kathleen.loadingreadyrun.com Hi Kathleen, on recent TTC Q&A you mentioned sharing a curated lofi beats playlist with @coachnelly.bsky.social any chance you’d share here on blusky too? thanks!! 🙏03 Jun 2025 11:47 +0000at://did:plc:oykhpsffhd33f5kv6kbaqlk2/app.bsky.feed.post/3lqp7se634s2qhttps://bsky.app/profile/calhoujd.bsky.social/post/3lqp3wfvnys27Hey @plasmidsaurus.bsky.social, have you heard of DinoCon? 🦖🦕 [contains quote post or other embedded content]03 Jun 2025 10:37 +0000at://did:plc:oykhpsffhd33f5kv6kbaqlk2/app.bsky.feed.post/3lqp3wfvnys27https://bsky.app/profile/calhoujd.bsky.social/post/3lpywaeehj22sCliPE now available in STAR Protocols: https://www.sciencedirect.com/science/article/pii/S2666166725002576?via%3Dihub [contains quote post or other embedded content]25 May 2025 14:57 +0000at://did:plc:oykhpsffhd33f5kv6kbaqlk2/app.bsky.feed.post/3lpywaeehj22shttps://bsky.app/profile/calhoujd.bsky.social/post/3lpywaeehj22sCliPE now available in STAR Protocols: https://www.sciencedirect.com/science/article/pii/S2666166725002576?via%3Dihub [contains quote post or other embedded content]25 May 2025 14:57 +0000at://did:plc:oykhpsffhd33f5kv6kbaqlk2/app.bsky.feed.post/3lpywaeehj22shttps://bsky.app/profile/calhoujd.bsky.social/post/3lpp4xqbkms2s@tychobrahe.bsky.social Have you been keeping tabs on Monster Train 2? Curious to hear your thoughts at some point!21 May 2025 17:31 +0000at://did:plc:oykhpsffhd33f5kv6kbaqlk2/app.bsky.feed.post/3lpp4xqbkms2shttps://bsky.app/profile/calhoujd.bsky.social/post/3lplyfhstpk2qSometimes I clone with 5+ year expired NEB enzymes just to feel something. https://media.tenor.com/8hpBr49k2qEAAAAC/dangerous-lets-get-dangerous.gif?hh=300&ww=40020 May 2025 11:31 +0000at://did:plc:oykhpsffhd33f5kv6kbaqlk2/app.bsky.feed.post/3lplyfhstpk2q