ImmunoHorizons is the #OpenAccess, fully peer-reviewed journal of The American Association of Immunologists, Inc. @immunologyaai.bsky.social Editor-in-Chief: Bonnie N. Dittel, Ph.D. https://bsky.app/profile/immunohorizons.bsky.socialhttps://bsky.app/profile/immunohorizons.bsky.social/post/3mled2vq5mk2m🚨 Paradigm Shift: New data in ImmunoHorizons suggests Hypermobile Ehlers–Danlos Syndrome (hEDS) includes innate immune dysfunction. This discovery, currently trending on @Altmetric, may redefine how we diagnose and treat hEDS moving forward. 🔗 ow.ly/nPMX50YWGFw.08 May 2026 18:06 +0000at://did:plc:pgdfyk73o4gc3vikfez2l76v/app.bsky.feed.post/3mled2vq5mk2mhttps://bsky.app/profile/immunohorizons.bsky.social/post/3mhvs532amc2mThis special issue of ImmunoHorizons, guest-edited by Dr. Yiliang Chen, highlights macrophages in the heart and discusses the role and impact of these cells in cardiovascular disease: ow.ly/vn2H50YyScp. https://ow.ly/vn2H50YyScp25 Mar 2026 19:10 +0000at://did:plc:pgdfyk73o4gc3vikfez2l76v/app.bsky.feed.post/3mhvs532amc2mhttps://bsky.app/profile/immunohorizons.bsky.social/post/3mbttdcryd223#ICYMI ImmunoHorizons is excited to share a Special Collection focused on avian influenza, featuring 3 reviews on factors impacting emergence and spread #OneHealth, characteristics of current H5N1 strains, and a method for vaccine design. Read more: ow.ly/6HN550XSZop. https://ow.ly/6HN550XSZop07 Jan 2026 15:55 +0000at://did:plc:pgdfyk73o4gc3vikfez2l76v/app.bsky.feed.post/3mbttdcryd223https://bsky.app/profile/immunohorizons.bsky.social/post/3mbc3a43lcs23When comparing salivary IgA antibody levels in those with vaccine-only vs vaccine-and-infection immunity, researchers found that IgA levels to spike and RBD are high in those with hybrid immunity but low in those with vaccine-only immunity. Read more: ow.ly/Xg8W50XNcci. https://ow.ly/Xg8W50XNcci31 Dec 2025 14:29 +0000at://did:plc:pgdfyk73o4gc3vikfez2l76v/app.bsky.feed.post/3mbc3a43lcs23https://bsky.app/profile/immunohorizons.bsky.social/post/3m5tnp25x6k2sResearchers sought to determine if pre-existing immunity to Cas9 from S. aureus or S. pyogenes was present or augmented in people with cystic fibrosis (CF), as a cure for #CF will likely require a gene therapy approach. Learn more in ImmunoHorizons: ow.ly/9MUj50XsYlK. https://ow.ly/9MUj50XsYlK17 Nov 2025 16:33 +0000at://did:plc:pgdfyk73o4gc3vikfez2l76v/app.bsky.feed.post/3m5tnp25x6k2shttps://bsky.app/profile/immunohorizons.bsky.social/post/3m4yaok4ebc2eResearchers found that exogenous type I interferons, a major downstream product of STING activation, also upregulate CCL22 in cancer cells via a STING-dependent mechanism and that exogenous IFN-β can directly activate STING. Learn more in ImmunoHorizons: ow.ly/C11i50Xmw7h https://ow.ly/C11i50Xmw7h06 Nov 2025 18:59 +0000at://did:plc:pgdfyk73o4gc3vikfez2l76v/app.bsky.feed.post/3m4yaok4ebc2ehttps://bsky.app/profile/immunohorizons.bsky.social/post/3m4vwormzg22kThe synergistic activity of LIGHT with other classical cytokines was observed to regulate transcription in pulmonary fibroblasts and suggests the involvement of LIGHT in shaping fibroblast phenotypes observed in chronic lung disease. 🔗 ow.ly/pGOn50Xmwlq. #OpenAccess https://ow.ly/pGOn50Xmwlq05 Nov 2025 20:55 +0000at://did:plc:pgdfyk73o4gc3vikfez2l76v/app.bsky.feed.post/3m4vwormzg22khttps://bsky.app/profile/immunohorizons.bsky.social/post/3m4su4xgv722kResearchers found that exogenous type I interferons, a major downstream product of STING activation, also upregulate CCL22 in cancer cells via a STING-dependent mechanism and that exogenous IFN-β can directly activate STING. Learn more in ImmunoHorizons: ow.ly/C11i50Xmw7h04 Nov 2025 15:31 +0000at://did:plc:pgdfyk73o4gc3vikfez2l76v/app.bsky.feed.post/3m4su4xgv722khttps://bsky.app/profile/immunohorizons.bsky.social/post/3lxx2uuct5c23New findings provide insight into the dynamics of various immune proteins present in breastmilk and highlight their pivotal roles in determining neonatal immune responses and microbial colonization at early stage. Read all about it: ow.ly/tGcu50W0eG3. #OpenAccess https://ow.ly/tGcu50W0eG303 Sep 2025 16:36 +0000at://did:plc:pgdfyk73o4gc3vikfez2l76v/app.bsky.feed.post/3lxx2uuct5c23