Movement disorders fellow @ University of Florida 🐊☀️ DM me your tract pictures 🧠 and videos of tremors 🌀https://bsky.app/profile/tremorswift.bsky.socialhttps://bsky.app/profile/tremorswift.bsky.social/post/3li6n2kku5k2nAbout half of patients with normal pressure hydrocephalus and parkinsonism have an abnormal DaT SPECT. But they do not have nigrosomal loss like in PD! Is their parkinsonism from mechanical disruption rather than neurodegeneration? Check out this cool study! https://www.neurology.org/doi/full/10.1212/WNL.0000000000213352?casa_token=8uIVRKxEyNUAAAAA%3AY5AKRKb784AZcFP_jagyTMyQAkg5DryIeFANOMCsQUXfnDt6_3J5UWu3uQOOMbTirQFH9mf9XLDwvvie15 Feb 2025 02:07 +0000at://did:plc:r5bgvsbtcsntptghslnw443a/app.bsky.feed.post/3li6n2kku5k2nhttps://bsky.app/profile/tremorswift.bsky.social/post/3lgtxadq3622uCheck out this paper I just dropped on non-motor phenotypes in Parkinson's disease with my bosses We found that patients with early REM sleep behavior in Parkinson's predicts WORSE non-motor symptoms. rdcu.be/d7QV229 Jan 2025 02:45 +0000at://did:plc:r5bgvsbtcsntptghslnw443a/app.bsky.feed.post/3lgtxadq3622uhttps://bsky.app/profile/tremorswift.bsky.social/post/3lgnoruuk7s2uDBS at the GPi and STN works well for dystonia, with most output reaching the Vo nucleus of the thalamus. Why not target that? Hashimoto and friends shared 4 cases of focal hand dystonia treated with thalamic DBS, showing most benefit near the Vo—same as for dystonic tremor! https://tinyurl.com/5n6urfhe26 Jan 2025 14:58 +0000at://did:plc:r5bgvsbtcsntptghslnw443a/app.bsky.feed.post/3lgnoruuk7s2uhttps://bsky.app/profile/tremorswift.bsky.social/post/3lg5dthhguc2p🔔 New drug for PD-MCI! 🔔 💊 M1 Receptor–Positive Allosteric Modulator. 👥 46 patients | 🕒 6 wks on /6 wksoff 🧷 Safe overall | 🚷 No gait changes 🧠 Cognitive improvement (?) Could it be real-life significant? Rivastigmine only works in PD dementia—this could be a first! tinyurl.com/rjxxwbxe20 Jan 2025 02:59 +0000at://did:plc:r5bgvsbtcsntptghslnw443a/app.bsky.feed.post/3lg5dthhguc2phttps://bsky.app/profile/tremorswift.bsky.social/post/3lfzse6tq722pWe love how effective DBS is to treat myoclonus dystonia syndrome. Patients with a SGCE mutation have one of the B E S T responses. Pauly M shared the case of KCCN2 mutation who did not improve significantly after GPi-DBS. Should we test SGCE-negative patients before DBS? tinyurl.com/msp6t8fa18 Jan 2025 17:08 +0000at://did:plc:r5bgvsbtcsntptghslnw443a/app.bsky.feed.post/3lfzse6tq722p