PhD AAZF ATSF FAHA. Associate Prof of Medicine at WashU, Co-Director BBSB PhD Program, Structural Biology, Molecular Mechanisms of Inflammation, lung disease, Alzheimer's Disease. Girlsdad. Outdoor Enthusiast.https://bsky.app/profile/tombrettlab.bsky.socialhttps://bsky.app/profile/tombrettlab.bsky.social/post/3lizatxftik2wGeorge was a great guy. I vividly remember meeting him at a mixer at the IUCr meeting in Seattle in '97 when I was a grad student. We had an hour long conversation about SHELX and crystallography and other things over beers. Both a deep thinker and down to earth guy. He leaves a big impact. [contains quote post or other embedded content]25 Feb 2025 16:10 +0000at://did:plc:rsxtdu7xd7oitm7tpuut55aq/app.bsky.feed.post/3lizatxftik2whttps://bsky.app/profile/tombrettlab.bsky.social/post/3lizarijtw22wFun fact about George Sheldrick: he wrote a paper on his SHELX software (that everyone uses for small molecule crystallography) in Acta Cryst A which caused the journal to go from Impact Factor 2 to an IF = 50. Spawned discussion on the relevance of IFs. Huge impact. [contains quote post or other embedded content]25 Feb 2025 16:09 +0000at://did:plc:rsxtdu7xd7oitm7tpuut55aq/app.bsky.feed.post/3lizarijtw22whttps://bsky.app/profile/tombrettlab.bsky.social/post/3lh74ngvfks2oOne of the joys of mentoring is getting a glimpse into your students “outside the lab” life. Got to see the amazing #LNYF25 performance including our amazing undergrad researcher Cynthia Zhi!02 Feb 2025 13:21 +0000at://did:plc:rsxtdu7xd7oitm7tpuut55aq/app.bsky.feed.post/3lh74ngvfks2ohttps://bsky.app/profile/tombrettlab.bsky.social/post/3lfiw4d5tkc2zBeautiful day for a snow hike with @jablab3.bsky.social ! Really amazing out there today!12 Jan 2025 00:00 +0000at://did:plc:rsxtdu7xd7oitm7tpuut55aq/app.bsky.feed.post/3lfiw4d5tkc2zhttps://bsky.app/profile/tombrettlab.bsky.social/post/3lffcwq5mlc2vI am so thrilled to share our latest collab with @jablab3.bsky.social ! Structural mapping of #TREM2 ligand interactions by #BLI. Led by Jessica Greven; thanks to big contributions by Josh Wydra, Cynthia Zhi,... https://molecularneurodegeneration.biomedcentral.com/articles/10.1186/s13024-024-00795-910 Jan 2025 13:39 +0000at://did:plc:rsxtdu7xd7oitm7tpuut55aq/app.bsky.feed.post/3lffcwq5mlc2vhttps://bsky.app/profile/tombrettlab.bsky.social/post/3lezdwspla22vAs a Minnesota native, I can’t pass up the opportunity for a snow run! Nice storm out there!05 Jan 2025 19:25 +0000at://did:plc:rsxtdu7xd7oitm7tpuut55aq/app.bsky.feed.post/3lezdwspla22vhttps://bsky.app/profile/tombrettlab.bsky.social/post/3lewhuhp2n227You know how the emails pile up over the holidays, and when you clean your inbox out by quick screen/delete, you hope you didn't get rid of something important? Just found out we @jablab3.bsky.social had a big paper accepted a week ago because the notice got deleted. Happy discoveries! https://media.tenor.com/dtC_OvFhrEwAAAAC/deleting-intensifies-linus-sebastian.gif?hh=420&ww=49804 Jan 2025 15:57 +0000at://did:plc:rsxtdu7xd7oitm7tpuut55aq/app.bsky.feed.post/3lewhuhp2n227https://bsky.app/profile/tombrettlab.bsky.social/post/3lepx4f33us2rAchievement unlocked! Chestnuts roasted on an open fire! Happy New Year to all!02 Jan 2025 01:42 +0000at://did:plc:rsxtdu7xd7oitm7tpuut55aq/app.bsky.feed.post/3lepx4f33us2rhttps://bsky.app/profile/tombrettlab.bsky.social/post/3lcxnxckoss2iWe are recruiting for Investigator (Tenure) track faculty @WUSTL in the Dept of Pathology and Immunology; Division of Lab and Genomic Medicine. Official details can be found here: https://pathology.wustl.edu/wp-content/uploads/2024/09/240823_LGMFacultySearch2024_FinalAd.pdf10 Dec 2024 16:29 +0000at://did:plc:rsxtdu7xd7oitm7tpuut55aq/app.bsky.feed.post/3lcxnxckoss2ihttps://bsky.app/profile/tombrettlab.bsky.social/post/3lcsxcrads22kBeautiful morning for #HotChocolate run with @jablab3.bsky.social and Jess Greven!08 Dec 2024 19:33 +0000at://did:plc:rsxtdu7xd7oitm7tpuut55aq/app.bsky.feed.post/3lcsxcrads22khttps://bsky.app/profile/tombrettlab.bsky.social/post/3lc7h2ukeyc2zThis is very interesting. And it DOES NOT mean that TREM2 is not a good target. It's a complex target. [contains quote post or other embedded content]01 Dec 2024 01:21 +0000at://did:plc:rsxtdu7xd7oitm7tpuut55aq/app.bsky.feed.post/3lc7h2ukeyc2z