https://bsky.app/profile/mathiaseder.bsky.socialhttps://bsky.app/profile/mathiaseder.bsky.social/post/3mhq3kzs74c2r🔥 How does CTCF shape enhancer–promoter communication? In our new preprint, we systematically test how the position and orientation of CTCF binding sites (CBSs) influence gene regulation at the mouse Sox2 locus. 🧪 full paper can be found here: https://www.biorxiv.org/content/10.64898/2026.03.16.711995v123 Mar 2026 12:43 +0000at://did:plc:sjyhmo35ihtj6bgmoermseec/app.bsky.feed.post/3mhq3kzs74c2rhttps://bsky.app/profile/mathiaseder.bsky.social/post/3lz72547jpk22✨Exciting news: the main story of my PhD is out in Science! Together with Christine Moene @cmoene.bsky.social, we explored what happens when you scramble the genome—revealing how Sox2’s position shapes enhancer activation. 📖 Read the full story here: https://www.science.org/doi/10.1126/science.ads655219 Sep 2025 14:09 +0000at://did:plc:sjyhmo35ihtj6bgmoermseec/app.bsky.feed.post/3lz72547jpk22