Neuroscientist-cell biologist, proteomics developer, deep learning collaborator, tackling brain disorders. PI @Duke. Chair of Cell Biology and Biochem. Founder, Triangle Protein Design. http://soderlinglab.cellbio.duke.eduhttps://bsky.app/profile/scottsoderling.bsky.socialhttps://bsky.app/profile/scottsoderling.bsky.social/post/3mnziitecgc2uFunny quote of the day. “No major life decisions within 30 days of: A meditation retreat A psychedelic experience Your first encounter with the latest Claude model” 😂11 Jun 2026 15:00 +0000at://did:plc:sojqh4hsampgc4lnkfevfb4a/app.bsky.feed.post/3mnziitecgc2uhttps://bsky.app/profile/scottsoderling.bsky.social/post/3mhcbl6bm6k2rMy lab was lucky to be able to help test Proteina-Complexa binders experimentally. We were blown away by the results. Congrats to our colleagues at NVIDIA! [contains quote post or other embedded content]18 Mar 2026 00:53 +0000at://did:plc:sojqh4hsampgc4lnkfevfb4a/app.bsky.feed.post/3mhcbl6bm6k2rhttps://bsky.app/profile/scottsoderling.bsky.social/post/3m74univyns2xThere is nothing sweeter than the first paper from your former postdoc’s own lab. Huge congratulations to Yudong and his lab! https://www.nature.com/articles/s41467-025-66120-004 Dec 2025 01:57 +0000at://did:plc:sojqh4hsampgc4lnkfevfb4a/app.bsky.feed.post/3m74univyns2xhttps://bsky.app/profile/scottsoderling.bsky.social/post/3m4qee3lah22lSounds very exciting [contains quote post or other embedded content]03 Nov 2025 15:43 +0000at://did:plc:sojqh4hsampgc4lnkfevfb4a/app.bsky.feed.post/3m4qee3lah22lhttps://bsky.app/profile/scottsoderling.bsky.social/post/3m46z4nkzz22jDeadline for applications- November 1st! [contains quote post or other embedded content]27 Oct 2025 18:07 +0000at://did:plc:sojqh4hsampgc4lnkfevfb4a/app.bsky.feed.post/3m46z4nkzz22jhttps://bsky.app/profile/scottsoderling.bsky.social/post/3m3zods26x22uPlease repost!!: We are searching for new AI-Bio faculty at Duke to be part of a new Discovery AI center. Looking for faculty who focus on pushing boundaries in ML model development in a highly interactive environment. DEADLINE for applications- Nov 1st!! https://www.nature.com/naturecareers/job/12844591/tenure-track-assistant-professor-position-ai-ml-for-cell-biology/25 Oct 2025 15:11 +0000at://did:plc:sojqh4hsampgc4lnkfevfb4a/app.bsky.feed.post/3m3zods26x22uhttps://bsky.app/profile/scottsoderling.bsky.social/post/3m2nhtzgbok2tCool new work- DynamicsPLM adds prot conformational dynamics to LMs: fuses seq with per-residue structure-token distributions from an ensemble (no averaging) → state-aware embeddings. Gains: +4% HumanPPI, +11% on multi-state proteins. Firing this up in the lab soon! https://www.biorxiv.org/content/10.1101/2025.10.06.680789v1.full.pdf08 Oct 2025 01:17 +0000at://did:plc:sojqh4hsampgc4lnkfevfb4a/app.bsky.feed.post/3m2nhtzgbok2thttps://bsky.app/profile/scottsoderling.bsky.social/post/3lybhgchhm22gDuke is recruiting a tenure-track Assistant Professor in AI/ML for Biology—joint Discovery AI Initiative × Cell Biology Search. Building models for protein design, single-cell/spatial omics, imaging, proteomics, genomics? Apply: academicjobsonline.org/ajo/jobs/30509 #hiring #AIforBio #CompBio07 Sep 2025 19:47 +0000at://did:plc:sojqh4hsampgc4lnkfevfb4a/app.bsky.feed.post/3lybhgchhm22ghttps://bsky.app/profile/scottsoderling.bsky.social/post/3lwp5djv3zs2yAnother milestone for the amazing Munjal lab! [contains quote post or other embedded content]18 Aug 2025 19:34 +0000at://did:plc:sojqh4hsampgc4lnkfevfb4a/app.bsky.feed.post/3lwp5djv3zs2yhttps://bsky.app/profile/scottsoderling.bsky.social/post/3lvsqzhlyos2xGreat work from Huanghe Yang’s lab in Duke Biochemistry. [contains quote post or other embedded content]07 Aug 2025 12:39 +0000at://did:plc:sojqh4hsampgc4lnkfevfb4a/app.bsky.feed.post/3lvsqzhlyos2xhttps://bsky.app/profile/scottsoderling.bsky.social/post/3lv4trdtffc2qCongrats James! Loved hearing about this at an earlier CZI meeting! [contains quote post or other embedded content]29 Jul 2025 19:29 +0000at://did:plc:sojqh4hsampgc4lnkfevfb4a/app.bsky.feed.post/3lv4trdtffc2qhttps://bsky.app/profile/scottsoderling.bsky.social/post/3ltryhf4huk2uI like o3 pro even better. [contains quote post or other embedded content]12 Jul 2025 18:29 +0000at://did:plc:sojqh4hsampgc4lnkfevfb4a/app.bsky.feed.post/3ltryhf4huk2u