Enzyme mechanisms, Structural Biology, Microbiome - Université Paris-Saclay, @univparissaclay.bsky.social, INRAE, @inrae-france.bsky.social, MICALIS institue, ChemSyBio Laboratory https://www.micalis.fr/equipe/chemsybio/https://bsky.app/profile/chemsybio.bsky.socialhttps://bsky.app/profile/chemsybio.bsky.social/post/3mmggn6e4vs2dHow B12-dependent radical SAM enzymes control stereochemistry and catalyze novel reactions and post-translational modifications? Out in @commsbio.nature.com https://www.nature.com/articles/s42003-026-10234-822 May 2026 07:40 +0000at://did:plc:stofwkflddiotem5kghbac5j/app.bsky.feed.post/3mmggn6e4vs2dhttps://bsky.app/profile/chemsybio.bsky.social/post/3mfmjnwdt322ahttps://doi.org/10.1039/D5SC04531B24 Feb 2026 15:54 +0000at://did:plc:stofwkflddiotem5kghbac5j/app.bsky.feed.post/3mfmjnwdt322ahttps://bsky.app/profile/chemsybio.bsky.social/post/3m6wr2kegus2shttps://www.inrae.fr/dossiers/lauriers-inrae01 Dec 2025 15:37 +0000at://did:plc:stofwkflddiotem5kghbac5j/app.bsky.feed.post/3m6wr2kegus2shttps://bsky.app/profile/chemsybio.bsky.social/post/3lrbvftnjic2zRadical SAM #enzyme & #antibiotic biosynthesis: ArsL, a novel [4Fe-4S] enzyme, cleaves the central S-adenosyl-L-methionine (SAM) cofactor to generate the 3-amino-3-carboxypropyl #radical instead of the 5′-deoxyadenosyl radical (5'-dA). Amazing team work! Check out: https://pubs.acs.org/doi/10.1021/jacs.5c0100610 Jun 2025 22:01 +0000at://did:plc:stofwkflddiotem5kghbac5j/app.bsky.feed.post/3lrbvftnjic2zhttps://bsky.app/profile/chemsybio.bsky.social/post/3lrajrrmgkc2sSpectroscopic and Biochemical Characterization of the Noncanonical Radical SAM Enzyme ArsL, Involved in Arsinothricin Biosynthesis | Journal of the American Chemical Society https://pubs.acs.org/doi/10.1021/jacs.5c0100610 Jun 2025 09:01 +0000at://did:plc:stofwkflddiotem5kghbac5j/app.bsky.feed.post/3lrajrrmgkc2shttps://bsky.app/profile/chemsybio.bsky.social/post/3ln6nrqraxk2oEvolutionary-scale prediction of atomic-level protein structure with a language model | Science https://www.science.org/doi/10.1126/science.ade257419 Apr 2025 17:26 +0000at://did:plc:stofwkflddiotem5kghbac5j/app.bsky.feed.post/3ln6nrqraxk2o