Focusing on telomere metabolism, innate immune signaling, cancer initiation, and proliferative boundaries; Salk Institutehttps://bsky.app/profile/karlsederlab.bsky.socialhttps://bsky.app/profile/karlsederlab.bsky.social/post/3lwh4tuelak22Another great read from the lab (this time with @joenassour.bsky.social) on how telomere crisis stands at the crossroads of cancer suppression and evolution 🧬 [contains quote post or other embedded content]15 Aug 2025 15:04 +0000at://did:plc:tbold2gw63csl622ahnvyfcx/app.bsky.feed.post/3lwh4tuelak22https://bsky.app/profile/karlsederlab.bsky.social/post/3lwh4e6mvyk2aOur lab’s latest “hot take” is out in Genes & Development! We argue for looking beyond senescence to understand how telomeres connect aging, tumor suppression, and inflammation. Great job @sambloom28.bsky.social! 👉 DOI: 10.1101/gad.353122.125 https://genesdev.cshlp.org/content/early/2025/07/11/gad.353122.12515 Aug 2025 14:55 +0000at://did:plc:tbold2gw63csl622ahnvyfcx/app.bsky.feed.post/3lwh4e6mvyk2ahttps://bsky.app/profile/karlsederlab.bsky.social/post/3li5jnrzu2k2kGreat opportunity for those looking for a faculty position! [contains quote post or other embedded content]14 Feb 2025 15:34 +0000at://did:plc:tbold2gw63csl622ahnvyfcx/app.bsky.feed.post/3li5jnrzu2k2khttps://bsky.app/profile/karlsederlab.bsky.social/post/3lhmjwfbvq22tHuge thanks to Hannah Trost, Gabriel Matos Rodriguez, Roger Greenberg, and Hilda Pickett for an amazing Mammalian DNA Repair GRS/GRC in Ventura! Already excited for the next one!07 Feb 2025 21:23 +0000at://did:plc:tbold2gw63csl622ahnvyfcx/app.bsky.feed.post/3lhmjwfbvq22thttps://bsky.app/profile/karlsederlab.bsky.social/post/3ldjulbae4k22With our lab’s inaugural Blue Sky post we celebrate our latest publication, a review in Nature Reviews Molecular Cell Biology (@natrevmcb.bsky.social) 🥳 Here, we review our current understanding of telomere biology, discussing differences between human and mouse. https://www.nature.com/articles/s41580-024-00800-517 Dec 2024 22:15 +0000at://did:plc:tbold2gw63csl622ahnvyfcx/app.bsky.feed.post/3ldjulbae4k22