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<rss version="2.0"><channel><description>Founder of El Arkhe: advanced multiomics training + accessible molecular science communication.&#xA;Visit:&#xA;🧬 Website https://el-arkhe.github.io/&#xA;回  Insta: https://www.instagram.com/elarkhe/&#xA;🌐 Personal https://cyntsc.github.io/</description><link>https://bsky.app/profile/cynthiasc.bsky.social</link><title>@cynthiasc.bsky.social - Cynthia | Multiomics specialist | Founder of El Arkhe</title><item><link>https://bsky.app/profile/cynthiasc.bsky.social/post/3mvaxngkfp22b</link><description>🧬 NUEVO Curso intensivo en línea:&#xA;&#xA;Procesamiento de datos scRNA-seq: cómputo en la nube con Cell Ranger y Agentes de IA&#xA;&#xA;📅 29 sep. y 1 oct.&#xA;⏱️ 6 h: demostración + práctica&#xA;🎓 Estudiantes: 30% de descuento&#xA;&#xA;Registro: luma.com/is86mj79&#xA;&#xA;#scRNAseq #Bioinformática</description><pubDate>11 Sep 2026 16:16 +0000</pubDate><guid isPermaLink="false">at://did:plc:tioa7y26eckd55twjbsff3fg/app.bsky.feed.post/3mvaxngkfp22b</guid></item><item><link>https://bsky.app/profile/cynthiasc.bsky.social/post/3msy4rhepj22g</link><description>Hola! Los invito/espero este J𝘂𝗲𝘃𝗲𝘀 𝟮𝟳 en el webinar &#34;𝙎𝙞𝙣𝙜𝙡𝙚-𝙘𝙚𝙡𝙡: 𝙀𝙡 𝙁𝙪𝙩𝙪𝙧𝙤 𝙙𝙚 𝙡𝙖 𝙂𝙚𝙣𝙤𝙢𝙞𝙘𝙖&#34;. Hablaré sobre la tecnología single-cell, sus aplicaciones y oportunidades en Latinoamérica. No falten! 🤗.&#xA;&#xA;Organizadores:&#xA;El Arkhe 🇲🇽 (Mx) + BioMaster 🇵🇪 (Perú)&#xA;Registro: luma.com/sipun2y4&#xA;&#xA;#SingleCell #LATAM&#xA;https://luma.com/sipun2y4</description><pubDate>13 Aug 2026 17:03 +0000</pubDate><guid isPermaLink="false">at://did:plc:tioa7y26eckd55twjbsff3fg/app.bsky.feed.post/3msy4rhepj22g</guid></item><item><link>https://bsky.app/profile/cynthiasc.bsky.social/post/3mpyyngplpk2t</link><description>Follow me for dates and not to miss the series.&#xA;&#xA;#Bioinformática #SingleCell #10xGenomics #CloudComputing&#xA;#InteligenciaArtificial</description><pubDate>06 Jul 2026 21:06 +0000</pubDate><guid isPermaLink="false">at://did:plc:tioa7y26eckd55twjbsff3fg/app.bsky.feed.post/3mpyyngplpk2t</guid></item><item><link>https://bsky.app/profile/cynthiasc.bsky.social/post/3mltupartss24</link><description>¿Sabías que en scRNA-seq 1 barcode ≠ 1 célula?&#xA;En datos droplet-based muchos barcodes pueden ser droplets vacíos o RNA ambiental.&#xA;Nuevo blog sobre cell calling y EmptyDrops 👇&#xA;https://cyntsc.github.io/single_cell_RNA-seq/cell_calling_scrnaseq/&#xA;&#xA;En comentarios:&#xA;Insta: @elarkhe&#xA;Visita nuestro taller&#xA;&#xA;#scRNAseq #10xGenomics #elarkhe</description><pubDate>14 May 2026 22:32 +0000</pubDate><guid isPermaLink="false">at://did:plc:tioa7y26eckd55twjbsff3fg/app.bsky.feed.post/3mltupartss24</guid></item><item><link>https://bsky.app/profile/cynthiasc.bsky.social/post/3mllvtycyrs2b</link><description>En scRNA-seq, detectar una célula no siempre es tan simple como contar UMIs.&#xA;Cell Ranger v3+ incorporó un enfoque inspirado en EmptyDrops para distinguir droplets vacíos de células reales, incluso con bajo RNA.&#xA;El jueves compartiré un breve blog sobre *cell calling*.&#xA;&#xA;#scRNAseq #CellRanger #ElArkhe</description><pubDate>11 May 2026 18:31 +0000</pubDate><guid isPermaLink="false">at://did:plc:tioa7y26eckd55twjbsff3fg/app.bsky.feed.post/3mllvtycyrs2b</guid></item><item><link>https://bsky.app/profile/cynthiasc.bsky.social/post/3mkqbav6wbc2d</link><description>¿𝗘𝘀𝘁𝗮𝘀 𝗲𝗺𝗽𝗲𝘇𝗮𝗻𝗱𝗼 𝗲𝗻 𝗮𝗻á𝗹𝗶𝘀𝗶𝘀 𝗱𝗲 𝗱𝗮𝘁𝗼𝘀 𝘀𝗶𝗻𝗴𝗹𝗲-𝗰𝗲𝗹𝗹 𝗥𝗡𝗔-𝘀𝗲𝗾 𝘆 𝗻𝗼 𝘁𝗲 𝗾𝘂𝗲𝗱𝗮 𝗰𝗹𝗮𝗿𝗮 𝗹𝗮 𝗱𝗶𝗳𝗲𝗿𝗲𝗻𝗰𝗶𝗮 𝗲𝗻𝘁𝗿𝗲 𝗮𝗿𝗰𝗵𝗶𝘃𝗼𝘀 .𝗵𝟱 𝘆 .𝗺𝘁𝘅?&#xA;Aplicar funciones “como recetas” sin entender qué estamos haciendo es muy común. Comprender los datos ayuda muchísimo a interpretar mejor. Blog: https://cyntsc.github.io/single_cell_RNA-seq/scRNAseq_h5_vs_mtx/</description><pubDate>30 Apr 2026 18:40 +0000</pubDate><guid isPermaLink="false">at://did:plc:tioa7y26eckd55twjbsff3fg/app.bsky.feed.post/3mkqbav6wbc2d</guid></item><item><link>https://bsky.app/profile/cynthiasc.bsky.social/post/3mggym2dhxs2s</link><description>𝗪𝗼𝗿𝗸𝗶𝗻𝗴 𝘄𝗶𝘁𝗵 𝘀𝗰𝗥𝗡𝗔-𝘀𝗲𝗾 𝗱𝗮𝘁𝗮?&#xA;One of the decisions when selecting a dataset is understanding which Chromium chemistry was used.&#xA;Understand 10X Genomics  𝗰𝗵𝗲𝗺𝗶𝘀𝘁𝗿𝗶𝗲𝘀: v3.1 vs GEM-X v4 and how they impact dataset selection.&#xA;A reference is on the first comment.&#xA;&#xA;#scRNAseq #10XGenomics #ElArkhe</description><pubDate>07 Mar 2026 04:31 +0000</pubDate><guid isPermaLink="false">at://did:plc:tioa7y26eckd55twjbsff3fg/app.bsky.feed.post/3mggym2dhxs2s</guid></item><item><link>https://bsky.app/profile/cynthiasc.bsky.social/post/3mgbfl2r5fk2h</link><description>¿Con qué frecuencia ponemos a prueba la robustez de nuestros pipelines de análisis single-cell?&#xA;Una estrategia práctica para ello es el submuestreo (subsampling), el cuál permite simular datasets más pequeños para evaluar decisiones analíticas.&#xA;Para quienes tengan interés:&#xA;https://github.com/el-arkhe/scrnaseq-workshop/blob/main/docs/main_docs/04_subsampling.md</description><pubDate>04 Mar 2026 23:07 +0000</pubDate><guid isPermaLink="false">at://did:plc:tioa7y26eckd55twjbsff3fg/app.bsky.feed.post/3mgbfl2r5fk2h</guid></item><item><link>https://bsky.app/profile/cynthiasc.bsky.social/post/3mfa4rmcm622k</link><description>Hola 👋&#xA;En LATAM el cómputo es un cuello de botella para analizar datos single-cell. El computo en la nube es una alternativa estrategica. &#xA;Comparto 3 mini-videos e introducción a 10X Genomics  on the Cloud. Mas links en comentarios.&#xA;📹 https://youtube.com/playlist?list=PL0Fk-VpvFmjKRhl69G3c6g6Y9O_VRUyai&amp;si=z43DOa06i6zMKndB &#xA;#SingleCell #CloudComputing #LATAM</description><pubDate>19 Feb 2026 17:32 +0000</pubDate><guid isPermaLink="false">at://did:plc:tioa7y26eckd55twjbsff3fg/app.bsky.feed.post/3mfa4rmcm622k</guid></item><item><link>https://bsky.app/profile/cynthiasc.bsky.social/post/3memva5gvmc23</link><description>Hola 👋&#xA;Preparando materiales de scRNA-seq, armé un notebook sobre Seurat v4 versus Seurat v5&#xA;Resumo los principales cambios conceptuales y estructurales que impactan scRNA-seq.&#xA;Si usas Seurat o piensas migrar a v5, puede serte útil.&#xA;&#xA;🔗 https://cyntsc.github.io/single_cell_RNA-seq/seurat_v4_v5/&#xA;&#xA;#scRNAseq #Seurat #SingleCell</description><pubDate>12 Feb 2026 01:56 +0000</pubDate><guid isPermaLink="false">at://did:plc:tioa7y26eckd55twjbsff3fg/app.bsky.feed.post/3memva5gvmc23</guid></item><item><link>https://bsky.app/profile/cynthiasc.bsky.social/post/3m6wzg26oqc2q</link><description>Aqui reactivando mi abandonada cuenta 😅 y compartiendo esta noticia:&#xA;Para interesados en agricultura, se ha presentado FX-Cell, un método que ayudan a superar la dificultad para obtener células individuales viables para scRNA-seq.  &#xA;https://www.nature.com/articles/s41592-025-02900-2 &#xA;#plantbiology #singlecell #CICY&#xA;https://lnkd.in/g_5-BKni</description><pubDate>01 Dec 2025 18:06 +0000</pubDate><guid isPermaLink="false">at://did:plc:tioa7y26eckd55twjbsff3fg/app.bsky.feed.post/3m6wzg26oqc2q</guid></item><item><link>https://bsky.app/profile/cynthiasc.bsky.social/post/3lqlkq5hysk2s</link><description>🔬 Diving into ATAC-seq workflows?&#xA;You&#39;ve likely heard about Seurat, Signac, MACS2, Cicero, and chromVAR—core components in many workflows.&#xA;Here’s a quick overview I put together that showcases different approaches used across recent studies.&#xA;https://youtu.be/R5P8mGMXuIg?si=1mVNQQLhq9kCee8X &#xA;#SingleCell #Epigenomics #LIBD</description><pubDate>02 Jun 2025 00:52 +0000</pubDate><guid isPermaLink="false">at://did:plc:tioa7y26eckd55twjbsff3fg/app.bsky.feed.post/3lqlkq5hysk2s</guid></item><item><link>https://bsky.app/profile/cynthiasc.bsky.social/post/3lofgiujzjc2c</link><description>¡Hola! 👋 Avances en nuestra investigación sobre la habenula humana, clave en motivación y estrés.&#xA;Usamos single-cell, epigenomics y spatial data para estudiarla.&#xA;Presentado en el 2025 Epigenomics Sciences Symposium (JHU). 🧠✨&#xA;#SingleCell #Epigenomics #LIBD</description><pubDate>05 May 2025 03:30 +0000</pubDate><guid isPermaLink="false">at://did:plc:tioa7y26eckd55twjbsff3fg/app.bsky.feed.post/3lofgiujzjc2c</guid></item><item><link>https://bsky.app/profile/cynthiasc.bsky.social/post/3ljna35iw4c2e</link><description>👉 Sharing a talk of the molecular neuroanatomical map of the human prefrontal cortex. This study integrates Visium Spatial data with snRNA-seq to map cell types and interactions across spatial domains. Le&#xA;Watch here: youtu.be/EhP5-mhw29w &#xA;Slides on video&#xA;Explore: research.libd.org/spatialDLPFC/&#xA;https://research.libd.org/spatialDLPFC/</description><pubDate>05 Mar 2025 14:50 +0000</pubDate><guid isPermaLink="false">at://did:plc:tioa7y26eckd55twjbsff3fg/app.bsky.feed.post/3ljna35iw4c2e</guid></item><item><link>https://bsky.app/profile/cynthiasc.bsky.social/post/3li3aayyazc2e</link><description>🚀 Interested in multimodal analysis with WNN in Seurat?&#xA;Check out my recent RStatClub presentation, where we dive into Jaccard, canonical gene expression, and Silhouette for clustering evaluation!&#xA;📺 Watch here: https://speakerdeck.com/cyntsc/clustering-methods-in-multiome-scrna-seq-and-scatac-seq&#xA;📑 Slides: https://www.youtube.com/watch?v=mE77X5G-3_8&#xA;#RStats</description><pubDate>13 Feb 2025 17:40 +0000</pubDate><guid isPermaLink="false">at://did:plc:tioa7y26eckd55twjbsff3fg/app.bsky.feed.post/3li3aayyazc2e</guid></item><item><link>https://bsky.app/profile/cynthiasc.bsky.social/post/3ld4jyoco3k2h</link><description>🚀 Sharing insights on ArchR, a powerful tool for single-cell chromatin accessibility analysis! 🎯 ArchR excels in large datasets and integrates scATACseq with scRNAseq for cutting-edge multi-modal studies.&#xA;🎥 Dive deeper with the video: https://youtu.be/XNZx5Dlp6jY?si=y3KXAzgC0iOMWGqW &#xA;#Bioinformatics #10xGenomics #LIBD</description><pubDate>12 Dec 2024 15:01 +0000</pubDate><guid isPermaLink="false">at://did:plc:tioa7y26eckd55twjbsff3fg/app.bsky.feed.post/3ld4jyoco3k2h</guid></item><item><link>https://bsky.app/profile/cynthiasc.bsky.social/post/3lb3m2c7unt2z</link><description>📊 Extraído de la presentación de @mbarse.bsky.social  en  nuestro Journal Club, abajo se resumen métricas compartidas y diferentes de Space Ranger para datos Visium 10x standard y Visium 10x Cytassist. Interesados en el análisis espacial y plataformas Visium?&#xA;🔗 Más: https://speakerdeck.com/manishabarse/exploring-spaceranger-summary-metrics</description><pubDate>16 Nov 2024 19:15 +0000</pubDate><guid isPermaLink="false">at://did:plc:tioa7y26eckd55twjbsff3fg/app.bsky.feed.post/3lb3m2c7unt2z</guid></item><item><link>https://bsky.app/profile/cynthiasc.bsky.social/post/3lb3kwf2qd22z</link><description>✨ Comparto desde nuestro `Journal Club` esta presentacion donde exploro `Feature selection and dimension reduction for single-cell RNAseq`. Si te interesa cómo aplicar modelos multinomiales en scRNAseq, ¡dale un vistazo! 🎥&#xA;🔗 Video: [GLM-PCA en acción](https://www.youtube.com/watch?v=8cyfUADgI7U&amp;t=1s)  &#xA;#LIBD #RNASeq</description><pubDate>16 Nov 2024 18:55 +0000</pubDate><guid isPermaLink="false">at://did:plc:tioa7y26eckd55twjbsff3fg/app.bsky.feed.post/3lb3kwf2qd22z</guid></item><item><link>https://bsky.app/profile/cynthiasc.bsky.social/post/3lahmijsy5t2h</link><description>Hi ! I am new here and I like to present my interests with this video from our Journal Club! This is an overview of the multiome analysis for scATACseq and scRNAseq using several &#xA;#CellRanger pipelines. This is inspired by our work at #LIBD and resources from 10x Genomics. https://youtu.be/fHVLi9-sftM?si=Hf1SDoSHI1l9_vkR</description><pubDate>08 Nov 2024 20:29 +0000</pubDate><guid isPermaLink="false">at://did:plc:tioa7y26eckd55twjbsff3fg/app.bsky.feed.post/3lahmijsy5t2h</guid></item></channel></rss>