We're the UK Promega life sciences team, sharing technical tips, our event info, science news, articles and blog posts.https://bsky.app/profile/promegauk.bsky.socialhttps://bsky.app/profile/promegauk.bsky.social/post/3mv32zc2n6f2iStep-by-step guide to #CellMetabolism research: from asking the right questions about cellular function to sample preparation and results interpretation Discover practical approaches for studying metabolic pathways by watching the video on YouTube: https://ow.ly/tuSb50Zzs3V #MetabolicResearch09 Sep 2026 08:00 +0000at://did:plc:tmfkravepnudb2ppuinmtuip/app.bsky.feed.post/3mv32zc2n6f2ihttps://bsky.app/profile/promegauk.bsky.social/post/3muykkeqvdx2dLooking to pull down HiBiT-tagged proteins? The HiBiT tag enables co-IP, interactome mapping and mass spec with native elution preserving complexes. High-affinity enrichment and gentle elution for Western blot, FACS and Mass Spec https://ow.ly/ySz150ZuWWl #Immunoprecipitation #Proteomics08 Sep 2026 08:00 +0000at://did:plc:tmfkravepnudb2ppuinmtuip/app.bsky.feed.post/3muykkeqvdx2dhttps://bsky.app/profile/promegauk.bsky.social/post/3muw2ebdqkk27Reliability matters. Spectrum® CE at Forensic Genomics Innovation Hub: still on their first capillary since Dec 2023 with 600+ injections Dr Caroline Parker shares how ease of use and reliability support critical forensic work on YouTube at https://ow.ly/2XHi50Zx0me #CapillaryElectrophoresis07 Sep 2026 08:05 +0000at://did:plc:tmfkravepnudb2ppuinmtuip/app.bsky.feed.post/3muw2ebdqkk27https://bsky.app/profile/promegauk.bsky.social/post/3muokvtwynb2vThe 11th International Conference on Legionella takes place next week, marking 50 years since the bacterium's discovery. Promega will be exhibiting—if you’re attending, visit the stand to meet the team and discover how our solutions could support your research. #Legionella202604 Sep 2026 08:40 +0000at://did:plc:tmfkravepnudb2ppuinmtuip/app.bsky.feed.post/3muokvtwynb2vhttps://bsky.app/profile/promegauk.bsky.social/post/3mulyicas7x2gMetabolic disease research is shifting from snapshots to dynamic, real-time measurement. Bioluminescent tools now capture multi-pathway responses. Read the blog at: https://ow.ly/WkxF50ZuXAA #MetabolicResearch #Bioluminescence03 Sep 2026 08:05 +0000at://did:plc:tmfkravepnudb2ppuinmtuip/app.bsky.feed.post/3mulyicas7x2ghttps://bsky.app/profile/promegauk.bsky.social/post/3mujhqvy2ef2gDetect HiBiT-tagged proteins by flow cytometry. Anti-HiBiT monoclonal antibody fluorophore conjugates offer sensitive signal from XFD dyes (no secondary needed), compatible with fixed & live-cell analysis. Green 488 & Far Red 647. More at: https://ow.ly/kPnN50ZuWMG #FlowCytometry02 Sep 2026 08:00 +0000at://did:plc:tmfkravepnudb2ppuinmtuip/app.bsky.feed.post/3mujhqvy2ef2ghttps://bsky.app/profile/promegauk.bsky.social/post/3mugxkibm742lReminder: free webinar tomorrow, Weds, 2 Sept 2026 at 3.00 p.m. (BST): Hold and Kill – RIPTAC Assay Strategy. Learn how NanoBRET® measures ternary complex formation for this breakthrough "hold-and-kill" approach in clinical trials. https://ow.ly/FCAG50ZwAel #TargetedProteinDegradation #RIPTAC01 Sep 2026 08:05 +0000at://did:plc:tmfkravepnudb2ppuinmtuip/app.bsky.feed.post/3mugxkibm742lhttps://bsky.app/profile/promegauk.bsky.social/post/3mu3466pqqw2lLumie's always ready when our LinkedIn Newsletter drops 👀 Fresh insights and industry updates delivered monthly. Subscribe on LinkedIn to join the community at: https://ow.ly/83aC50ZG5Nc #NewsletterCommunity #LifeSciences27 Aug 2026 14:55 +0000at://did:plc:tmfkravepnudb2ppuinmtuip/app.bsky.feed.post/3mu3466pqqw2lhttps://bsky.app/profile/promegauk.bsky.social/post/3mu2f7ulls62nFc Effector Insight: Integrated workflow from lead generation to lot release. Download the Fc Receptors guide covering Lumit® binding assays, ADCC/ADCP Reporter Assays & HiBiT® Target Cell Killing Bioassays at: https://ow.ly/boyr50Zgb4A #AntibodyTherapeutics #FcReceptors27 Aug 2026 08:05 +0000at://did:plc:tmfkravepnudb2ppuinmtuip/app.bsky.feed.post/3mu2f7ulls62nhttps://bsky.app/profile/promegauk.bsky.social/post/3mtxuqwqfbo2sFree webinar Weds, 2 Sept, 3pm BST: Hold and Kill: An Integrated Assay Strategy for RIPTAC, an Emerging Induced-Proximity Modality Learn how NanoBRET® measures ternary complex formation and #assay strategies for #RIPTAC developability. Co-hosted with ICE Bioscience - https://ow.ly/6Wlj50ZwzYj 26 Aug 2026 08:05 +0000at://did:plc:tmfkravepnudb2ppuinmtuip/app.bsky.feed.post/3mtxuqwqfbo2shttps://bsky.app/profile/promegauk.bsky.social/post/3mtvdzdpr3p2jMost protein detection kills cells first. HiBiT bioluminescence works differently – 11 amino acid tag gives direct, quantitative readout in live cells. Perfect for protein secretion, degrader-induced loss and receptor trafficking. More at: https://ow.ly/4izp50ZuKXs #CellBiology #DrugDiscovery25 Aug 2026 08:00 +0000at://did:plc:tmfkravepnudb2ppuinmtuip/app.bsky.feed.post/3mtvdzdpr3p2jhttps://bsky.app/profile/promegauk.bsky.social/post/3mtstt3zyqa22Consistent results matter for QC and lot release Promega's Thaw-and-Use cells are validated for potency testing across therapeutic targets: FcγR-targeting antibodies, Checkpoint Inhibitors, and Cytokine-GF Receptors. Batch sizes to 1,000 vials, stringent QC https://ow.ly/J1Ap50ZgaJF #Bioassays24 Aug 2026 08:05 +0000at://did:plc:tmfkravepnudb2ppuinmtuip/app.bsky.feed.post/3mtstt3zyqa22https://bsky.app/profile/promegauk.bsky.social/post/3mtirxgdmss2eEarlier this year at AACR 2026, Promega presented Lumit® hKi-67 Immunoassay for cell proliferation (Poster #477) Missed it? It's worth catching up with over the summer! The bioluminescent method optimises screening across suspension, adherent and 3D cancer models https://ow.ly/GRPf50ZgjMV #AACR 20 Aug 2026 08:05 +0000at://did:plc:tmfkravepnudb2ppuinmtuip/app.bsky.feed.post/3mtirxgdmss2ehttps://bsky.app/profile/promegauk.bsky.social/post/3mtgba2ivxu2hcAMP is a primary second messenger from GPCR activation. Lumit® cAMP Immunoassay: quantitative, no-wash bioluminescent readout directly from cell lysates. No washing, no transfer steps. Learn more at: https://ow.ly/kmE650ZuKzp #GPCR #CellSignalling19 Aug 2026 08:00 +0000at://did:plc:tmfkravepnudb2ppuinmtuip/app.bsky.feed.post/3mtgba2ivxu2hhttps://bsky.app/profile/promegauk.bsky.social/post/3mtdqzl4zdj2oJoin us tomorrow at 3.00 p.m. BST: for our free webinar on scaling ocean biodiversity monitoring with environmental DNA, with speakers from the Minderoo OceanOmics Centre at the University of Western Australia and Promega. Register at: https://ow.ly/S7Ok50ZhsnI #eDNA #MarineConservation18 Aug 2026 08:05 +0000at://did:plc:tmfkravepnudb2ppuinmtuip/app.bsky.feed.post/3mtdqzl4zdj2ohttps://bsky.app/profile/promegauk.bsky.social/post/3mtbaknafx62wIn manufacturing, reproducibility is everything. Yet cell thawing and expansion introduce major variability. Promega's assay-ready Thaw-and-Use cells arrive ready for immediate use, supporting faster, more consistent workflows from day one. https://ow.ly/FhMz50Zgapp #Bioassays #Manufacturing17 Aug 2026 08:05 +0000at://did:plc:tmfkravepnudb2ppuinmtuip/app.bsky.feed.post/3mtbaknafx62whttps://bsky.app/profile/promegauk.bsky.social/post/3msy237x2gz2tGPCR internalisation controls receptor availability. Nano-Glo® HiBiT Extracellular Detection System quantifies cell-surface proteins in real time using antibody-free HiBiT tagging to measure internalisation and recycling. More at: https://ow.ly/vUuQ50ZuI0O #HiBiT #ReceptorInternalisation13 Aug 2026 16:15 +0000at://did:plc:tmfkravepnudb2ppuinmtuip/app.bsky.feed.post/3msy237x2gz2thttps://bsky.app/profile/promegauk.bsky.social/post/3msuo7zu5ci22What can a single drop of seawater reveal about our oceans? Join us on 19 August 2026 at 3.00 pm BST for a free webinar with the University of Western Australia, exploring how #eDNA workflows are scaling marine biodiversity monitoring - https://ow.ly/cb7550ZhsKI #MarineConservation 12 Aug 2026 08:05 +0000at://did:plc:tmfkravepnudb2ppuinmtuip/app.bsky.feed.post/3msuo7zu5ci22https://bsky.app/profile/promegauk.bsky.social/post/3mss5r4czoy2hOperator-dependent cell handling causes inconsistent batch performance and complicates tech transfer. Promega's assay-ready Thaw-and-Use cells support process consistency by design, reducing variability across teams and sites. More at: https://ow.ly/KO8450Z4O7Q #Bioassays #ThawAndUse11 Aug 2026 08:05 +0000at://did:plc:tmfkravepnudb2ppuinmtuip/app.bsky.feed.post/3mss5r4czoy2hhttps://bsky.app/profile/promegauk.bsky.social/post/3mspncbthbw22Advanced in vitro #neurotoxicity testing is critical for drug safety Our new Application Note with NETRI shows LDH-Glo™ Cytotoxicity Assay enables sensitive measurements in 2D & 3D microfluidic systems for non-destructive organoid monitoring Download at: https://ow.ly/VJIO50ZgeQ2 #OrganOnChip10 Aug 2026 08:05 +0000at://did:plc:tmfkravepnudb2ppuinmtuip/app.bsky.feed.post/3mspncbthbw22https://bsky.app/profile/promegauk.bsky.social/post/3msflh6pzau2gLumie's practising for a Netflix documentary: "The Emotional Weight of Running Promega UK's Social Channels" 😊 Want more of Lumie's adventures? Follow us on Instagram @promega_uk for behind-the-scenes fun and lab life insights! #BehindTheScenes #TeamLife06 Aug 2026 08:05 +0000at://did:plc:tmfkravepnudb2ppuinmtuip/app.bsky.feed.post/3msflh6pzau2ghttps://bsky.app/profile/promegauk.bsky.social/post/3msakiojyhb2kDrug development slows when early workflows don't support commercial realities. Promega's assay-ready Thaw-and-Use cells support commercial thinking early, moving faster from development to manufacturing without re-engineering. More at: https://ow.ly/8RN950Z4NBA #Bioassays #ThawAndUse04 Aug 2026 08:05 +0000at://did:plc:tmfkravepnudb2ppuinmtuip/app.bsky.feed.post/3msakiojyhb2khttps://bsky.app/profile/promegauk.bsky.social/post/3ms622dxury2hNanoBiT® PPI measures #protein-protein interactions in live cells in real time. GloMax® Galaxy imaging visualises where & how interactions unfold within cells. Example: CX3CR1 recruitment shifts from membrane to intracellular puncta during internalisation - https://ow.ly/8ks850ZuEWQ #NanoBiT 03 Aug 2026 08:05 +0000at://did:plc:tmfkravepnudb2ppuinmtuip/app.bsky.feed.post/3ms622dxury2hhttps://bsky.app/profile/promegauk.bsky.social/post/3mrty62kpaj2hDoes your compound engage its GPCR target in living cells? NanoBRET® Target Engagement measures this directly Fluorescent tracer competes with your compound for NanoLuc-tagged GPCR, giving true cellular IC₅₀. No radioactivity, no membrane prep More at: https://ow.ly/zOXF50Zl3hS #NanoBRET #GPCR30 Jul 2026 08:05 +0000at://did:plc:tmfkravepnudb2ppuinmtuip/app.bsky.feed.post/3mrty62kpaj2hhttps://bsky.app/profile/promegauk.bsky.social/post/3mrrhp5einy25With rising biologic drug development, robust analytical methods are essential #PeptideMapping ensures therapeutic antibody quality Proteases with orthogonal cleavage improve sequence coverage, enhance characterisation, and reduce instrument time What challenges do you face? Let’s discuss!29 Jul 2026 08:05 +0000at://did:plc:tmfkravepnudb2ppuinmtuip/app.bsky.feed.post/3mrrhp5einy25https://bsky.app/profile/promegauk.bsky.social/post/3mrpbc2xgez2gReminder: Free webinar tomorrow 4pm BST on Live Bioluminescence Imaging for real-time gene expression in human development. Learn how endogenously tagged bioluminescent reporters work in 2D and 3D stem cell models. Register at: https://ow.ly/zrH450ZjYrx #DevelopmentalBiology28 Jul 2026 11:05 +0000at://did:plc:tmfkravepnudb2ppuinmtuip/app.bsky.feed.post/3mrpbc2xgez2ghttps://bsky.app/profile/promegauk.bsky.social/post/3mroxaaxokp2dNew application note: CellTiter-Glo® 3D integrated with MO:BOT automation transforms 3D culture. Less variability, higher signals, better data from seeding to endpoint assay. Facing reproducibility challenges? This is worth reading. https://ow.ly/vHZj50Zl2z3 #3DCellCulture #LabAutomation28 Jul 2026 08:05 +0000at://did:plc:tmfkravepnudb2ppuinmtuip/app.bsky.feed.post/3mroxaaxokp2dhttps://bsky.app/profile/promegauk.bsky.social/post/3mrmgrcoedk2pExploring TDCC as a mechanism of action? Promega's complete workflow: Lumit® assays for cytokines, TDCC #Bioassays for T-cell-driven killing, HiBiT assays for target-cell death Clear data from screening to lot release for immune-oncology therapeutics More at: https://ow.ly/xyAC50Zga3m #TDCC27 Jul 2026 08:05 +0000at://did:plc:tmfkravepnudb2ppuinmtuip/app.bsky.feed.post/3mrmgrcoedk2phttps://bsky.app/profile/promegauk.bsky.social/post/3mrcevmigpc2gExploring ADCP as a mechanism of action? Promega's complete workflow: Lumit® assays for FcγR engagement, ADCP Bioassays for phagocytosis readouts, HiBiT assays for target-cell loss. Clear data from screening to lot release. See our website for more information. #Biologics #ADCP23 Jul 2026 08:05 +0000at://did:plc:tmfkravepnudb2ppuinmtuip/app.bsky.feed.post/3mrcevmigpc2ghttps://bsky.app/profile/promegauk.bsky.social/post/3mra6imguoe2iFree webinar Wed 29 July, 4pm BST: Live Bioluminescence Imaging for real-time gene expression in human development. Learn how endogenously tagged bioluminescent reporters work in 2D & 3D stem cell models. Register: https://ow.ly/Az2j50ZjY5k #DevelopmentalBiology22 Jul 2026 11:05 +0000at://did:plc:tmfkravepnudb2ppuinmtuip/app.bsky.feed.post/3mra6imguoe2i