Associate Professor at the university of Oslohttps://bsky.app/profile/chymkowitchlab.bsky.socialhttps://bsky.app/profile/chymkowitchlab.bsky.social/post/3mhfucqibss2kExcited to share that our latest research has been published in @narjournal.bsky.social Read the article here: https://academic.oup.com/nar/article/54/6/gkag232/8528805 Congratulations to Patrizia Nothnagel and many thanks to all people involved including Nolwenn Briand, Bjørn Steen Skålhegg and @amathelier.bsky.social.19 Mar 2026 11:07 +0000at://did:plc:udoy2bicdfcanlea2ytk62ol/app.bsky.feed.post/3mhfucqibss2khttps://bsky.app/profile/chymkowitchlab.bsky.social/post/3lznzqd4zp22c🌟 Congratulations to my PhD student Patrizia Nothnagel! 🌟 Patrizia won the "SUMO" poster award at the 2025 EMBO workshop "SUMOylation: From Discovery to Translation" in La Grande-Motte, France. Her work has paid off, and I am proud of her.25 Sep 2025 13:12 +0000at://did:plc:udoy2bicdfcanlea2ytk62ol/app.bsky.feed.post/3lznzqd4zp22chttps://bsky.app/profile/chymkowitchlab.bsky.social/post/3lvqrvfnq5k2jI am delighted to share a publication in @natcomms.nature.com. IRX3, linked to obesity via the FTO locus, influences fat vs bone cell fate. It is the result of a wonderful collaboration between S. Dankel, G. Mellgren @unibergen.bsky.social and my lab @biovitenskap.bsky.social 🍾 👉 rdcu.be/ezA5o https://rdcu.be/ezA5o06 Aug 2025 17:49 +0000at://did:plc:udoy2bicdfcanlea2ytk62ol/app.bsky.feed.post/3lvqrvfnq5k2jhttps://bsky.app/profile/chymkowitchlab.bsky.social/post/3loyggwmr522oWe are extending the application deadline for this post-doc position! Do not miss the opportunity to join an exciting project in a dynamic and collaborative research environment. @igbmc.bsky.social @pasteur.fr @univbordeaux.bsky.social @uio.no #epigenetics #cellfate #SUMOylation @ncmbm.bsky.social https://www.jobbnorge.no/en/available-jobs/job/279366/postdoctoral-research-fellow-in-molecular-biology-and-epigenetics12 May 2025 16:49 +0000at://did:plc:udoy2bicdfcanlea2ytk62ol/app.bsky.feed.post/3loyggwmr522ohttps://bsky.app/profile/chymkowitchlab.bsky.social/post/3lnn435zwak2gTotipotent-like cells in early mouse embryos reorganize their genome via Z-DNA and Zscan4-driven interactions to form a “Z compartment” first supporting ZGA and later compartmentalisation to safeguard the totipotent-like state. Chromatin plasticity at its finest! https://www.biorxiv.org/content/10.1101/2025.03.18.643869v125 Apr 2025 11:19 +0000at://did:plc:udoy2bicdfcanlea2ytk62ol/app.bsky.feed.post/3lnn435zwak2ghttps://bsky.app/profile/chymkowitchlab.bsky.social/post/3lniar2yi4k2uWe’re Hiring! I am seeking a Pos-doc Researcher in Molecular Biology and Epigenetics. Join our team @biovitenskap.bsky.social @uio.no to explore how SUMOylation regulates epigenetic fate, gene expression, 3D-genome and chromatin during adipogenesis, with implications for obesity and cancer research.23 Apr 2025 13:00 +0000at://did:plc:udoy2bicdfcanlea2ytk62ol/app.bsky.feed.post/3lniar2yi4k2uhttps://bsky.app/profile/chymkowitchlab.bsky.social/post/3lmqz4u322k2yThis study is a very elegant characterisation of the epigenetic and transcriptional divergence between white and beige adipocytes. Very useful to those studying the epigenetic mechanisms supporting cellular reprogramming. https://www.biorxiv.org/content/10.1101/2025.03.28.645896v114 Apr 2025 07:12 +0000at://did:plc:udoy2bicdfcanlea2ytk62ol/app.bsky.feed.post/3lmqz4u322k2yhttps://bsky.app/profile/chymkowitchlab.bsky.social/post/3ljpjmsfqx22iOur recent in vivo study reveals that inhibiting SUMOylation with TAK-981 disrupts fat accumulation, leading to impaired adipogenesis and increased immune cell infiltration in perigonadal white adipose tissue. https://www.tandfonline.com/doi/full/10.1080/21623945.2025.247410706 Mar 2025 12:46 +0000at://did:plc:udoy2bicdfcanlea2ytk62ol/app.bsky.feed.post/3ljpjmsfqx22ihttps://bsky.app/profile/chymkowitchlab.bsky.social/post/3lgcld4kzw22jMy group @biovitenskap.bsky.social is #hiring a Post-doc in bioinformatics and biostatistics to work on #epigenetic memory in stem cells and during cell reprogramming. The position is co-supervised by @amathelier.bsky.social from @nordicembl.bsky.social22 Jan 2025 04:56 +0000at://did:plc:udoy2bicdfcanlea2ytk62ol/app.bsky.feed.post/3lgcld4kzw22jhttps://bsky.app/profile/chymkowitchlab.bsky.social/post/3lgbnpg2zy22tThanks for sharing the first of the two positions that we will propose in the next 6 months @biovitenskap.bsky.social Stay tuned! [contains quote post or other embedded content]21 Jan 2025 20:06 +0000at://did:plc:udoy2bicdfcanlea2ytk62ol/app.bsky.feed.post/3lgbnpg2zy22thttps://bsky.app/profile/chymkowitchlab.bsky.social/post/3ldpwbrntys2b🎄 What a fantastic Christmas gift! Our #FRIPRO application on the regulation of epigenetic fate by #SUMOylation has been awarded 12MNOK by the Research Council of Norway!20 Dec 2024 08:01 +0000at://did:plc:udoy2bicdfcanlea2ytk62ol/app.bsky.feed.post/3ldpwbrntys2bhttps://bsky.app/profile/chymkowitchlab.bsky.social/post/3lddl5pk2bs2oThousands of people have donated to rebuild Notre-Dame de Paris, including me. But there are hundreds of heritage sites that deserve our attention. Why not make small donations to support projects like this surprising pagoda in the heart of France? https://www.fondation-patrimoine.org/les-projets/pagode-du-petit-jonas-a-ambazac/8763715 Dec 2024 10:10 +0000at://did:plc:udoy2bicdfcanlea2ytk62ol/app.bsky.feed.post/3lddl5pk2bs2ohttps://bsky.app/profile/chymkowitchlab.bsky.social/post/3lcp6ygtqgk2tSuperb story studying obesity from an epigenetic memory angle rdcu.be/d2Jun https://rdcu.be/d2Jun07 Dec 2024 07:39 +0000at://did:plc:udoy2bicdfcanlea2ytk62ol/app.bsky.feed.post/3lcp6ygtqgk2thttps://bsky.app/profile/chymkowitchlab.bsky.social/post/3lbzz3fdjtc2cA superbe afternoon sun over the Oslo fjord during the retreat of the BMB section. Thanks to all speakers and poster presenters for their contribution 👏👍 @biovitenskap.bsky.social28 Nov 2024 21:28 +0000at://did:plc:udoy2bicdfcanlea2ytk62ol/app.bsky.feed.post/3lbzz3fdjtc2c