Interested in how macrophages count and measure, and macrophage-cancer interactions. Assoc prof at UCSB https://morrisseylab.mcdb.ucsb.edu/https://bsky.app/profile/mmorrissey.bsky.socialhttps://bsky.app/profile/mmorrissey.bsky.social/post/3m3fr3kq52c2oWe have TWO papers out in @jcb.org this month! 🎉 First, @kirstin-rollins.bsky.social showed that macrophages nibble adherent target cells, like the ones found in solid tumors, instead of phagocytosing. Amazing movies from @sareenfiaz.bsky.social https://doi.org/10.1083/jcb.20250203417 Oct 2025 17:07 +0000at://did:plc:vwtz25mjigbcliym2trg6b53/app.bsky.feed.post/3m3fr3kq52c2ohttps://bsky.app/profile/mmorrissey.bsky.social/post/3m2u43dfvis2iCould not agree more 😁 [contains quote post or other embedded content]10 Oct 2025 16:35 +0000at://did:plc:vwtz25mjigbcliym2trg6b53/app.bsky.feed.post/3m2u43dfvis2ihttps://bsky.app/profile/mmorrissey.bsky.social/post/3lhytaf5rqk2xWyatt Miller's thesis project is on bioRxiv! We describe the signaling cascade that allows the 'Don't Eat Me' signal CD47 to inhibit phagocytosis. https://www.biorxiv.org/content/10.1101/2025.02.11.637707v112 Feb 2025 18:42 +0000at://did:plc:vwtz25mjigbcliym2trg6b53/app.bsky.feed.post/3lhytaf5rqk2xhttps://bsky.app/profile/mmorrissey.bsky.social/post/3lhtppylqq223Excited to share @kirstin-rollins.bsky.social thesis project! 🥳Why do macrophages sometimes eat a whole cell, and sometimes just nibble off pieces? We found that if the target cell is stuck to a substrate or part of a 3D tissue, the macrophage nibbles instead of phagocytosing the whole cell. [contains quote post or other embedded content]10 Feb 2025 17:56 +0000at://did:plc:vwtz25mjigbcliym2trg6b53/app.bsky.feed.post/3lhtppylqq223https://bsky.app/profile/mmorrissey.bsky.social/post/3lgsxwzrzu22cExtremely grateful to Damon Runyon for this funding, especially with todays news on NIH grants. See a green macrophage nibbling on a pink cancer cell 👇 [contains quote post or other embedded content]28 Jan 2025 17:25 +0000at://did:plc:vwtz25mjigbcliym2trg6b53/app.bsky.feed.post/3lgsxwzrzu22chttps://bsky.app/profile/mmorrissey.bsky.social/post/3letzwcazp226Macrophages need to adjust their appetite based on whats happening around them... but how to make a macrophage hungrier? Annalise Bond assembled a list of biophysical and biochemical parameters that can tune phagocytosis. @jcellsci.bsky.social @biologists.bsky.social https://doi.org/10.1242/jcs.263513 https://journals.biologists.com/jcs/article/138/1/JCS263513/364914/Biochemical-and-biophysical-mechanisms-macrophages?guestAccessKey=db67024f-d4cc-4589-afd5-2e55f43584df03 Jan 2025 16:42 +0000at://did:plc:vwtz25mjigbcliym2trg6b53/app.bsky.feed.post/3letzwcazp226https://bsky.app/profile/mmorrissey.bsky.social/post/3ldefhfqcik2sAt #Ascb? Check our Wyatt Millers poster on CD47 today at 1:30 (b696) or his talk Monday at 5:30 p in the immune cell biology subgroup!15 Dec 2024 18:01 +0000at://did:plc:vwtz25mjigbcliym2trg6b53/app.bsky.feed.post/3ldefhfqcik2shttps://bsky.app/profile/mmorrissey.bsky.social/post/3lcntcnh23k2qSuch a great study showing that target biophysics govern the decision to trogocytose (nibble) vs phagocytose [contains quote post or other embedded content]06 Dec 2024 18:38 +0000at://did:plc:vwtz25mjigbcliym2trg6b53/app.bsky.feed.post/3lcntcnh23k2qhttps://bsky.app/profile/mmorrissey.bsky.social/post/3kzjtwifddo2cA light appetizer makes macrophages hungrier for their next meal. My lab's first grad student @AnnaliseBond 's first paper is out now in @dev_cell !! https://authors.elsevier.com/sd/article/S1534-5807(24)00457-X12 Aug 2024 15:51 +0000at://did:plc:vwtz25mjigbcliym2trg6b53/app.bsky.feed.post/3kzjtwifddo2chttps://bsky.app/profile/mmorrissey.bsky.social/post/3kxxlieb5o22dInterested in immune cell biology? Join us for ASCB #cellbio2024 in the subgroup organized by Minna Roh Johnson, Marcus Taylor and me! Just two weeks left to submit your abstract https://www.ascb.org/cellbio2024/abstracts/23 Jul 2024 16:07 +0000at://did:plc:vwtz25mjigbcliym2trg6b53/app.bsky.feed.post/3kxxlieb5o22d