Senior Group Leader at Josep Carreras Institute. Chromatin; Nucleal metabolism; Leukemia; MDS; Drug Targets; Histone variants. Posting about the lab and the wider scientific community. More info about us here: www.buschbecklab.orghttps://bsky.app/profile/marcusbuschbeck.bsky.socialhttps://bsky.app/profile/marcusbuschbeck.bsky.social/post/3mlbovf5sck2wPlease RT: Opportunity to join us as technician! We are looking for a technician to support us in our projects in MPN and other myeloid malignancies using epigenomics on primary samples and PDX mouse models. Where: @carrerasijc.bsky.social When: Anytime. What: 👉https://sl1nk.com/0ekf3z607 May 2026 17:00 +0000at://did:plc:wasanfdkiesn2i4glix7ftyt/app.bsky.feed.post/3mlbovf5sck2whttps://bsky.app/profile/marcusbuschbeck.bsky.social/post/3mhs4xrg3tk2rMEET THE LAB! Paula, Jeannine, Marina and Marcus are in Finland attending the @EHA_Hematology Research Conference #EHAReCon2026 "From cradle to grave: normal and malignant hematopoiesis in young and aged settings". For our presentations, come and check out Poster 44 & Poster 68!24 Mar 2026 08:13 +0000at://did:plc:wasanfdkiesn2i4glix7ftyt/app.bsky.feed.post/3mhs4xrg3tk2rhttps://bsky.app/profile/marcusbuschbeck.bsky.social/post/3mgv33dl2ok2dGreat opportunity for Senescence aficionados to share results and network in Spain's most beautiful university town! [contains quote post or other embedded content]12 Mar 2026 18:52 +0000at://did:plc:wasanfdkiesn2i4glix7ftyt/app.bsky.feed.post/3mgv33dl2ok2dhttps://bsky.app/profile/marcusbuschbeck.bsky.social/post/3mdimtsy6p226Check out the new profile page of the lab on LinkedIN! We will post news about: - Changes in the team composition - Opportunities - Where to meet us - Preprints, publications and theses Indeed, we have been growing. Find out more here: https://www.linkedin.com/company/buschbeck-lab/?viewAsMember=true28 Jan 2026 15:50 +0000at://did:plc:wasanfdkiesn2i4glix7ftyt/app.bsky.feed.post/3mdimtsy6p226https://bsky.app/profile/marcusbuschbeck.bsky.social/post/3m5sxvl4rt22oLast opportunity to join the NUCLEAR network as PhD student in a Biotech environment! [contains quote post or other embedded content]17 Nov 2025 10:03 +0000at://did:plc:wasanfdkiesn2i4glix7ftyt/app.bsky.feed.post/3m5sxvl4rt22ohttps://bsky.app/profile/marcusbuschbeck.bsky.social/post/3m5sxuij6hk2oLast opportunity to join the NUCLEAR network as PhD student! [contains quote post or other embedded content]17 Nov 2025 10:03 +0000at://did:plc:wasanfdkiesn2i4glix7ftyt/app.bsky.feed.post/3m5sxuij6hk2ohttps://bsky.app/profile/marcusbuschbeck.bsky.social/post/3m4fp4aqrqs2oNEW PAPER Out in Science Advances: We have dissected the physiological role of all macroH2A histone variants. In mice, loss of macroH2A1.1 specifically results in profound metabolic reprogramming and kidney pathology. DOI: 10.1126/sciadv.adz1242 Thread 1/730 Oct 2025 09:56 +0000at://did:plc:wasanfdkiesn2i4glix7ftyt/app.bsky.feed.post/3m4fp4aqrqs2ohttps://bsky.app/profile/marcusbuschbeck.bsky.social/post/3m3x56xepv227True in 9 out of 10 cases. [contains quote post or other embedded content]24 Oct 2025 14:58 +0000at://did:plc:wasanfdkiesn2i4glix7ftyt/app.bsky.feed.post/3m3x56xepv227https://bsky.app/profile/marcusbuschbeck.bsky.social/post/3m3mjg4ndjk2iMEET THE LAB! This week our postdoc René Winkler will attend the @febspress.bsky.social workshop 'Molecular and cellular pathways of aging in hematopoiesis' on Crete, Greece. René will present work led by @shubhra.bsky.social on how cohesin mutations impact MDS progression.20 Oct 2025 09:38 +0000at://did:plc:wasanfdkiesn2i4glix7ftyt/app.bsky.feed.post/3m3mjg4ndjk2ihttps://bsky.app/profile/marcusbuschbeck.bsky.social/post/3m3m4zpxic22uMEET THE LAB Today Marina Farkas is attending the "Molecular Haemopoiesis" meeting at the Francis Crick Institute in London, UK. A gathering of researchers studying #blood development, with a particular focus on blood stem cell biology, gene regulation and #leukaemia.20 Oct 2025 05:56 +0000at://did:plc:wasanfdkiesn2i4glix7ftyt/app.bsky.feed.post/3m3m4zpxic22uhttps://bsky.app/profile/marcusbuschbeck.bsky.social/post/3m2mmro45vk2bAdios and salut to a pioneer! Sir John Gurdon studied the requirements and barriers of #reprogramming. Highly relevant for us, with his PhD student Vincent Pasque he showed that macroH2A is part of the epigenetic barrier inhibiting reprogramming. Our thoughts are with his family and friends. [contains quote post or other embedded content]07 Oct 2025 17:13 +0000at://did:plc:wasanfdkiesn2i4glix7ftyt/app.bsky.feed.post/3m2mmro45vk2bhttps://bsky.app/profile/marcusbuschbeck.bsky.social/post/3m2bwzswpkk2zNEW TEAM MEMBER! We welcome Bedri Batuhan Yaman to the group. Bedri will study the role of nuclear metabolism in #AML. He is co-supervised by @florherbstein.bsky.social and fellow of the MSCA @nucleardn.bsky.social. Bedri is alumnus of @viblifesciences.bsky.social (Belgium) and NeuroBM (Turkey).03 Oct 2025 11:17 +0000at://did:plc:wasanfdkiesn2i4glix7ftyt/app.bsky.feed.post/3m2bwzswpkk2zhttps://bsky.app/profile/marcusbuschbeck.bsky.social/post/3m27a3ssdqc27FAREWELL! After 6 month of Master research, Francesco B. Ciriscioli is returning to his home university in Triest, Italy. Thank you, Francesco, for your interesting results and for having enriched our group with your kind personality. We wish you all the best!02 Oct 2025 09:21 +0000at://did:plc:wasanfdkiesn2i4glix7ftyt/app.bsky.feed.post/3m27a3ssdqc27https://bsky.app/profile/marcusbuschbeck.bsky.social/post/3m24qvogmq22xGreat weather at daytime and northern lights at night time illuminate the scientific kick-off of the #HubMOL #MSCA doctoral network. On Someroy, a small island at the Artic Coast of Norway, we learn about the dual role of molecules such as NAD and SAM in signalling and metabolism.01 Oct 2025 09:44 +0000at://did:plc:wasanfdkiesn2i4glix7ftyt/app.bsky.feed.post/3m24qvogmq22xhttps://bsky.app/profile/marcusbuschbeck.bsky.social/post/3lzzognqa5s2zMEET THE LAB! During the next 3 days, I am in northern Norway at the kick-off workshop of the HubMOL consortium. This MSCA doctoral network coordinated by Ines Heiland, University of Tromsø, aims to gain a better understanding of the dual role of NAD, CoA and co. in metabolism and signalling.30 Sep 2025 04:22 +0000at://did:plc:wasanfdkiesn2i4glix7ftyt/app.bsky.feed.post/3lzzognqa5s2zhttps://bsky.app/profile/marcusbuschbeck.bsky.social/post/3lyg7havp5c2lNEW DOCTOR IN TOWN! Congratulations to Lejuan Shi from Sonia Forcales' lab who has defended her thesis today. As chair of her defense committee with Concepcio Soler and @tanyavavouri.bsky.social, I had the opportunity to discuss with Lejuan about the role of lncRNAs in cancer.09 Sep 2025 17:08 +0000at://did:plc:wasanfdkiesn2i4glix7ftyt/app.bsky.feed.post/3lyg7havp5c2lhttps://bsky.app/profile/marcusbuschbeck.bsky.social/post/3lxfa4vgonk2qNEW LAB MEMBER! We welcome ‪@florherbstein.bsky.social who is joining us as a‬ ‪@carrerasleaders.bsky.social‬ Postdoctoral Fellow. She is alumni of #IBioBA-MPSP and the University of Buenos Aires.‬‬ She will study how nuclear metabolism influences proliferation and therapy resistance in AML.27 Aug 2025 14:22 +0000at://did:plc:wasanfdkiesn2i4glix7ftyt/app.bsky.feed.post/3lxfa4vgonk2qhttps://bsky.app/profile/marcusbuschbeck.bsky.social/post/3lwtqvibvhc2bLast 10 days to apply for this PhD position in medicinal chemistry! [contains quote post or other embedded content]20 Aug 2025 15:34 +0000at://did:plc:wasanfdkiesn2i4glix7ftyt/app.bsky.feed.post/3lwtqvibvhc2bhttps://bsky.app/profile/marcusbuschbeck.bsky.social/post/3luroti2mtk2hOPPORTUNITY for a CHEMIST to JOIN US Are you interested in: 👍 Computer-aided ligand design 👍 Organic synthesis 👍 Biomedicine 👍 Drug development 👍 A multidisciplinary team 👍 And a PhD in Barcelona Then check this out! rb.gy/nc3lf3 https://rb.gy/nc3lf325 Jul 2025 09:02 +0000at://did:plc:wasanfdkiesn2i4glix7ftyt/app.bsky.feed.post/3luroti2mtk2hhttps://bsky.app/profile/marcusbuschbeck.bsky.social/post/3lumsmi6mds2p'NEW' LAB MEMBER! Our 2022 technician trainee Julia Ledesma is back. Julia is using the summer break of her biology studies at the University of Barcelona to help us advancing our projects as auxiliary technician. Thanks a lot, Julia.23 Jul 2025 10:26 +0000at://did:plc:wasanfdkiesn2i4glix7ftyt/app.bsky.feed.post/3lumsmi6mds2phttps://bsky.app/profile/marcusbuschbeck.bsky.social/post/3lthsbsn3tc2cPoster presentations by professors and group leaders for politicians. Maybe something we scientists should do in every country to make sure our elected representatives know what we are aiming to do. [contains quote post or other embedded content]08 Jul 2025 17:12 +0000at://did:plc:wasanfdkiesn2i4glix7ftyt/app.bsky.feed.post/3lthsbsn3tc2c