Principal Scientist @Genentech | Translational research & biomarker development in prostate cancer. Passionate about bridging science and patient impact.https://bsky.app/profile/denizgoekbuget.bsky.socialhttps://bsky.app/profile/denizgoekbuget.bsky.social/post/3m7o7h5w46k2jWe’re hiring now: 2026 Translational Medicine – Oncology Intern (Genentech, SSF). Work on epigenetics, multi-omics, and biomarker discovery for targeted therapies. PhD students in relevant fields encouraged to apply. Details and how to apply: https://roche.wd3.myworkdayjobs.com/ROG-A2O-GENE/job/South-San-Francisco/XMLNAME-2026-Summer-Intern---Translational-Medicine_202512-13142010 Dec 2025 23:26 +0000at://did:plc:wvuapee52ko4d7go6ruvpwnz/app.bsky.feed.post/3m7o7h5w46k2jhttps://bsky.app/profile/denizgoekbuget.bsky.social/post/3m4a4ztntzk2zI’m excited to share that I’ve joined Genentech as a Principal Scientist in Translational Medicine, where I’ll focus on biomarker development and translational research in prostate cancer. I’m looking forward to working with incredible colleagues to advance innovative therapies for patients.28 Oct 2025 04:50 +0000at://did:plc:wvuapee52ko4d7go6ruvpwnz/app.bsky.feed.post/3m4a4ztntzk2zhttps://bsky.app/profile/denizgoekbuget.bsky.social/post/3ly23ze7qn22dCheck out our new BioRepli-seq technique in this invited article related to our recent KMT2C/KMT2D replication timing study ⬇️. We use click chemistry–based biotinylation and on-bead library prep to comprehensively profile genome-wide DNA replication timing. 🔗 star-protocols.cell.com/protocols/4439 [contains quote post or other embedded content]04 Sep 2025 21:35 +0000at://did:plc:wvuapee52ko4d7go6ruvpwnz/app.bsky.feed.post/3ly23ze7qn22dhttps://bsky.app/profile/denizgoekbuget.bsky.social/post/3lrvkzu5fec2vThis one hits different these days: https://www.youtube.com/watch?v=MBH-169OHNg #TheFlamingLips #ResearchLife18 Jun 2025 17:49 +0000at://did:plc:wvuapee52ko4d7go6ruvpwnz/app.bsky.feed.post/3lrvkzu5fec2vhttps://bsky.app/profile/denizgoekbuget.bsky.social/post/3li3vocmq6s2wFor decades, NIH funding has fueled breakthroughs in cancer, heart disease and more. But a new policy puts progress at risk. We need Congress to oppose this abrupt change. Join me in emailing lawmakers today! #SaveNIHresearch bit.ly/4hxmfsK https://bit.ly/4hxmfsK14 Feb 2025 00:03 +0000at://did:plc:wvuapee52ko4d7go6ruvpwnz/app.bsky.feed.post/3li3vocmq6s2whttps://bsky.app/profile/denizgoekbuget.bsky.social/post/3lhek5zs7m22v🚨 New Paper Alert! 🚨 Our latest study on KMT2C/KMT2D (mutated in 20% of cancers) reveals a new function for H3K4me1 in regulating DNA replication timing (RT) and origin activity during cell state transitions. Check it out: https://www.cell.com/cell-reports/fulltext/S2211-1247(25)00043-9. More info ⬇️04 Feb 2025 17:06 +0000at://did:plc:wvuapee52ko4d7go6ruvpwnz/app.bsky.feed.post/3lhek5zs7m22vhttps://bsky.app/profile/denizgoekbuget.bsky.social/post/3lcm5avhbns2xReally enjoyed this rigorous mechanistic study on the multifaceted principles of genome-wide heterochromatin maintenance during pluripotency from the Zaret lab (not on Bsky). Congrats to the authors: https://www.nature.com/articles/s41556-024-01547-z#Bib106 Dec 2024 02:30 +0000at://did:plc:wvuapee52ko4d7go6ruvpwnz/app.bsky.feed.post/3lcm5avhbns2xhttps://bsky.app/profile/denizgoekbuget.bsky.social/post/3lasfqwsbi22tGlad to see @robertblelloch.bsky.social over here, outstanding mentor and scientist. Follow him, and also check out his lab account: @rblellochlab.bsky.social13 Nov 2024 03:28 +0000at://did:plc:wvuapee52ko4d7go6ruvpwnz/app.bsky.feed.post/3lasfqwsbi22thttps://bsky.app/profile/denizgoekbuget.bsky.social/post/3klalzbidco2iThank you to International Society for Stem Cell Research and Kendra Prutton for representing me and my research. I am proud to be part of this impactful and enriching community. https://www.isscr.org/isscr-news/member-spotlight-deniz-goekbuget-phd12 Feb 2024 19:43 +0000at://did:plc:wvuapee52ko4d7go6ruvpwnz/app.bsky.feed.post/3klalzbidco2ihttps://bsky.app/profile/denizgoekbuget.bsky.social/post/3kg3azt7x652iExciting news! 🧬🎄Our latest preprint on a new MLL3/MLL4 function in DNA replication timing is out: https://biorxiv.org/content/10.1101/2023.12.07.569680v1 Grateful for this teamwork with Ryan Boileau, Kayla Lenshoek, Robert Blelloch. @UCSF, @UCSFstemcell, @UCSFUrology, @UCSFCancer09 Dec 2023 01:37 +0000at://did:plc:wvuapee52ko4d7go6ruvpwnz/app.bsky.feed.post/3kg3azt7x652i