Professor at TUM - Postdoc in the Rinn & Meissner Lab (Harvard) - PhD in Denise Barlow's lab (CeMM)https://bsky.app/profile/dandergassen.bsky.socialhttps://bsky.app/profile/dandergassen.bsky.social/post/3mrs7oos3ys27It was a pleasure to write this Comment with @sarahhoelzl.bsky.social before she "escaped" the lab after a very successful Ph.D. 😊 https://www.nature.com/articles/s41580-026-01007-629 Jul 2026 15:14 +0000at://did:plc:xg444eaxtlds4ebqmohy6ffu/app.bsky.feed.post/3mrs7oos3ys27https://bsky.app/profile/dandergassen.bsky.social/post/3mluot3fg3k2mWe are offering Postdoc & PhD positions 🥼 If you are interested in the intersection of X chromosome inactivation, epigenetics, aging, sex-biased disease, and allele-specific multi-omics, feel free to reach out or share this with interested candidates. More info: https://portal.mytum.de/jobs/wissenschaftler/NewsArticle_20260510_14145815 May 2026 06:19 +0000at://did:plc:xg444eaxtlds4ebqmohy6ffu/app.bsky.feed.post/3mluot3fg3k2mhttps://bsky.app/profile/dandergassen.bsky.social/post/3mkpk7jcnp22rProud of the lab team 🎉 @alessia-karasani.bsky.social won 1st prize for her poster 🏆 and @sarahhoelzl.bsky.social presented her PhD work at #EESSexDifferences.30 Apr 2026 11:48 +0000at://did:plc:xg444eaxtlds4ebqmohy6ffu/app.bsky.feed.post/3mkpk7jcnp22rhttps://bsky.app/profile/dandergassen.bsky.social/post/3m6gzhlymic2tGiving a seminar today @ethz.ch on our new X-reactivation findings during aging—back at the institute where I started my PhD 10 years ago. Can’t wait to see some familiar faces!25 Nov 2025 09:25 +0000at://did:plc:xg444eaxtlds4ebqmohy6ffu/app.bsky.feed.post/3m6gzhlymic2thttps://bsky.app/profile/dandergassen.bsky.social/post/3m5et3sopp22xNew paper from the lab: we’re using long-read sequencing to disentangle isoform complexity at allele-specific loci 🧬💡 Here, we combine the PacBio Iso-Seq workflow with the established WhatsHap phasing approach to assign long reads to the correct allele in polymorphic F1 mouse hybrids.11 Nov 2025 19:00 +0000at://did:plc:xg444eaxtlds4ebqmohy6ffu/app.bsky.feed.post/3m5et3sopp22xhttps://bsky.app/profile/dandergassen.bsky.social/post/3m3vu4nwtf22xCracking the code of the non-coding genome via allele-specific genomics? Can we link non-coding elements—like lncRNAs and enhancers—to their protein-coding target genes, and in doing so, connect overlapping non-coding disease variants to their protein-coding counterparts?24 Oct 2025 02:43 +0000at://did:plc:xg444eaxtlds4ebqmohy6ffu/app.bsky.feed.post/3m3vu4nwtf22xhttps://bsky.app/profile/dandergassen.bsky.social/post/3lrvjg2kyw226We are so happy to be on the cover @sarahhoelzl.bsky.social 🎉 The cover depicts the Three Fates, who manipulate the threads of life and death. The Fates are shown as three older women, unraveling the threads of the inactive X chromosome during aging. https://www.nature.com/nataging/volumes/5/issues/618 Jun 2025 17:20 +0000at://did:plc:xg444eaxtlds4ebqmohy6ffu/app.bsky.feed.post/3lrvjg2kyw226https://bsky.app/profile/dandergassen.bsky.social/post/3lo7mbnprgc2yI’m incredibly proud to share the results of our lab’s first project, leading to the exciting discovery – Aging promotes reactivation of the Barr body at distal chromosome regions – now published in @nataging.nature.com! 🔗 tinyurl.com/3jkzzy7d02 May 2025 19:57 +0000at://did:plc:xg444eaxtlds4ebqmohy6ffu/app.bsky.feed.post/3lo7mbnprgc2yhttps://bsky.app/profile/dandergassen.bsky.social/post/3ljpfwh7c7s2pI am super proud to share the first Andergassen Lab preprint! Here, we introduce a new framework to decode the non-coding genome, led by the outstanding work of @hasenbeint.bsky.social and co-authors Sarah Hölzl, Stefan Engelhardt @tum.de👇🧵06 Mar 2025 11:40 +0000at://did:plc:xg444eaxtlds4ebqmohy6ffu/app.bsky.feed.post/3ljpfwh7c7s2p