antibodies, viruses, cryo-EM -- habitually curious -- postdoc at Stanfordhttps://bsky.app/profile/delaitsch.bsky.socialhttps://bsky.app/profile/delaitsch.bsky.social/post/3mtjjrz522s2kFourier transform is top of that list for me. I think my understanding and execution of structural biology projects improved dramatically late-PhD when I had a better grasp of thinking in terms of Fourier space. [contains quote post or other embedded content]20 Aug 2026 15:11 +0000at://did:plc:y62l7jvpidvu6fdsc5af5635/app.bsky.feed.post/3mtjjrz522s2khttps://bsky.app/profile/delaitsch.bsky.social/post/3mdy2hwti522jbNAb #007. #HIV #antibody #V3 #avidity #cryo-EM https://www.nature.com/articles/s41590-025-02385-3 Cryo-EM revealed trimers with 0, 1, 2, or 3 Fabs bound -leading to some surprising insights into avidity and neutralization that make 007 stand out for more than just its name. (1/5)03 Feb 2026 19:04 +0000at://did:plc:y62l7jvpidvu6fdsc5af5635/app.bsky.feed.post/3mdy2hwti522jhttps://bsky.app/profile/delaitsch.bsky.social/post/3mcvjf3w6yc2kWas such a great class last year! I’d highly recommend to ppl getting into tomography [contains quote post or other embedded content]21 Jan 2026 01:28 +0000at://did:plc:y62l7jvpidvu6fdsc5af5635/app.bsky.feed.post/3mcvjf3w6yc2khttps://bsky.app/profile/delaitsch.bsky.social/post/3m2khgtyqoc23There's a new best-in-class HIV-1 antibody out today! Happy to have contributed to the structural characterization of this, and two other distinct VRC01-class bNAbs isolated from a single individual. https://www.nature.com/articles/s41590-025-02286-506 Oct 2025 20:32 +0000at://did:plc:y62l7jvpidvu6fdsc5af5635/app.bsky.feed.post/3m2khgtyqoc23https://bsky.app/profile/delaitsch.bsky.social/post/3m262kbyvdc2xFrom what I gather, CXCR4 (previously called fusin) was identified as a co-receptor for HIV nearly 30 years ago (pubmed.ncbi.nlm.nih.gov/8629022/). Nice to see a structure, and interesting to see it was done with HIV-2 gp120. [contains quote post or other embedded content]01 Oct 2025 22:09 +0000at://did:plc:y62l7jvpidvu6fdsc5af5635/app.bsky.feed.post/3m262kbyvdc2xhttps://bsky.app/profile/delaitsch.bsky.social/post/3ljdeuw7bp22oInstant classic 🤯 [contains quote post or other embedded content]01 Mar 2025 16:49 +0000at://did:plc:y62l7jvpidvu6fdsc5af5635/app.bsky.feed.post/3ljdeuw7bp22ohttps://bsky.app/profile/delaitsch.bsky.social/post/3lcwizfj3wk2v100 years ago, De Broglie published his thesis, "On the Theory of Quanta". The ideas in it catalyzed the development of electron microscopy, though Ernst Ruska was apparently unaware of De Broglie's "material waves" when he and Max Knoll first started toying with the electron microscope.10 Dec 2024 05:28 +0000at://did:plc:y62l7jvpidvu6fdsc5af5635/app.bsky.feed.post/3lcwizfj3wk2vhttps://bsky.app/profile/delaitsch.bsky.social/post/3lcl6zjctps2zOut now in its final form! These antibodies had us stumped for quite some time. https://www.nature.com/articles/s41541-024-01038-005 Dec 2024 17:29 +0000at://did:plc:y62l7jvpidvu6fdsc5af5635/app.bsky.feed.post/3lcl6zjctps2zhttps://bsky.app/profile/delaitsch.bsky.social/post/3lbswwg7pl22yCaltech looking nice tonight!26 Nov 2024 02:01 +0000at://did:plc:y62l7jvpidvu6fdsc5af5635/app.bsky.feed.post/3lbswwg7pl22y