Healthspan is the first online medical clinic dedicated to fighting age-related diseases and increasing human performance by fighting cellular senescence.https://bsky.app/profile/healthspanmed.bsky.socialhttps://bsky.app/profile/healthspanmed.bsky.social/post/3moiyphz5vx2mHealthspan is hiring a Head of Growth.17 Jun 2026 19:00 +0000at://did:plc:zi7xsjosic4o7kbk53aen4sv/app.bsky.feed.post/3moiyphz5vx2mhttps://bsky.app/profile/healthspanmed.bsky.social/post/3mlcges6bwj22🧬 Is aging just wear-and-tear, or is it a built-in flaw in our biological “software”? Dr. João Pedro de Magalhães proposes an interesting perspective: our DNA is the hardware, while the epigenome acts as software. Over time, this “software” may become maladaptive, driving the aging Read more 🧵👇08 May 2026 00:00 +0000at://did:plc:zi7xsjosic4o7kbk53aen4sv/app.bsky.feed.post/3mlcges6bwj22https://bsky.app/profile/healthspanmed.bsky.social/post/3mjvys6mioz2ySometimes a biomarker reflects adaptation—not pathology. Highly trained athletes can show HbA1c levels in the prediabetic range despite excellent metabolic health. We examine how exercise physiology creates this paradox—and why context matters more than static thresholds. 🧵👇20 Apr 2026 08:00 +0000at://did:plc:zi7xsjosic4o7kbk53aen4sv/app.bsky.feed.post/3mjvys6mioz2yhttps://bsky.app/profile/healthspanmed.bsky.social/post/3mhznmdfmd52g1. Resistance training doesn't just build muscle. It clears senescent cells—dysfunctional "zombie" cells that accumulate with age and drive inflammation, tissue dysfunction, and frailty. New research shows 5 months of resistance training reduced senescent cells in adipose tissue by 60%.🧵👇27 Mar 2026 08:00 +0000at://did:plc:zi7xsjosic4o7kbk53aen4sv/app.bsky.feed.post/3mhznmdfmd52ghttps://bsky.app/profile/healthspanmed.bsky.social/post/3mhko5nijkv2bWhy do hair loss treatments often plateau? New research suggests the answer may lie inside the follicle’s internal environment. As senescence accumulates and autophagy slows, follicles become less responsive—even to established therapies. https://www.gethealthspan.com/research/article/rapamycin-for-hair-loss-research https://gethealthspan.com/undefined/research/article/rapamycin-for-hair-loss-research21 Mar 2026 09:00 +0000at://did:plc:zi7xsjosic4o7kbk53aen4sv/app.bsky.feed.post/3mhko5nijkv2bhttps://bsky.app/profile/healthspanmed.bsky.social/post/3mhj77mdwhb2h🧬 Is aging just wear-and-tear, or is it a built-in flaw in our biological “software”? Dr. João Pedro de Magalhães proposes an interesting perspective: our DNA is the hardware, while the epigenome acts as software. Over time, this “software” may become maladaptive, driving the aging Read more 🧵👇20 Mar 2026 19:00 +0000at://did:plc:zi7xsjosic4o7kbk53aen4sv/app.bsky.feed.post/3mhj77mdwhb2hhttps://bsky.app/profile/healthspanmed.bsky.social/post/3mhgoqsogky2hNAD⁺ fuels metabolism and DNA repair. Levels decline sharply with age. Preclinical results are compelling — but human data remain mixed. Our latest Research Review examines where NAD⁺ restoration stands ↓ https://www.gethealthspan.com/research/article/nad-boosters https://gethealthspan.com/undefined/research/article/nad-boosters19 Mar 2026 19:00 +0000at://did:plc:zi7xsjosic4o7kbk53aen4sv/app.bsky.feed.post/3mhgoqsogky2hhttps://bsky.app/profile/healthspanmed.bsky.social/post/3mgxlxarfrn2cWhat if GLP-1 and GIP therapies intersect with the hallmarks of aging? Recent clinical data show improvements across cardiovascular, renal, hepatic, and even cognitive domains—patterns that extend beyond glucose control. https://www.gethealthspan.com/research/article/glp1-longevity-connection https://gethealthspan.com/undefined/research/article/glp1-longevity-connection13 Mar 2026 19:00 +0000at://did:plc:zi7xsjosic4o7kbk53aen4sv/app.bsky.feed.post/3mgxlxarfrn2chttps://bsky.app/profile/healthspanmed.bsky.social/post/3mgo2u4i63y2r1. Rapamycin suppresses mTORC1—the pathway that drives muscle growth. So how could it possibly preserve muscle with aging? The answer lies in understanding what happens when mTOR becomes chronically overactive in aging tissue—and why strength, not just size, determines independence. 🧵👇10 Mar 2026 00:00 +0000at://did:plc:zi7xsjosic4o7kbk53aen4sv/app.bsky.feed.post/3mgo2u4i63y2rhttps://bsky.app/profile/healthspanmed.bsky.social/post/3mgj5be3ecy2nAt age 34, something shifts inside the ovaries. Fertility declines more steeply. Embryo quality drops. IVF success rates fall. The usual explanation is chromosomal errors. But a new multi-omics study suggests the root cause may be metabolic—not genetic.08 Mar 2026 01:00 +0000at://did:plc:zi7xsjosic4o7kbk53aen4sv/app.bsky.feed.post/3mgj5be3ecy2nhttps://bsky.app/profile/healthspanmed.bsky.social/post/3mghky2fsgo2hGLP-1 and dual incretin therapies don’t just lower weight. They recalibrate nutrient sensing, reduce chronic inflammation, and influence mitochondrial function across organs. New Research Review ↓ https://www.gethealthspan.com/research/article/glp1-longevity-connection https://gethealthspan.com/undefined/research/article/glp1-longevity-connection07 Mar 2026 10:00 +0000at://did:plc:zi7xsjosic4o7kbk53aen4sv/app.bsky.feed.post/3mghky2fsgo2hhttps://bsky.app/profile/healthspanmed.bsky.social/post/3mgg422sxuf2hWhat if hair loss isn’t just about hormones—but about regeneration failing? Emerging studies link hair follicle stem cell activity to autophagy and mitochondrial health. New Research Review ↓ https://www.gethealthspan.com/research/article/rapamycin-for-hair-loss-research https://gethealthspan.com/undefined/research/article/rapamycin-for-hair-loss-research06 Mar 2026 20:00 +0000at://did:plc:zi7xsjosic4o7kbk53aen4sv/app.bsky.feed.post/3mgg422sxuf2hhttps://bsky.app/profile/healthspanmed.bsky.social/post/3mg6knhemdf2z🚨 How Endogenous Fructose Fuels Inflammation and Accelerates Aging—Watch Now https://www.youtube.com/watch?v=vBoiRMm0mdk03 Mar 2026 20:00 +0000at://did:plc:zi7xsjosic4o7kbk53aen4sv/app.bsky.feed.post/3mg6knhemdf2zhttps://bsky.app/profile/healthspanmed.bsky.social/post/3mg5zuuy7hs2c1. A central question in gerontology is why “young blood” appears to enhance tissue repair in older organisms. Research by Drs. Irina and Michael Conboy at UC Berkeley has provided compelling evidence through parabiosis experiments, wherein an older mouse is surgically joined to a younger one. 🧵👇03 Mar 2026 15:00 +0000at://did:plc:zi7xsjosic4o7kbk53aen4sv/app.bsky.feed.post/3mg5zuuy7hs2chttps://bsky.app/profile/healthspanmed.bsky.social/post/3mfwzahdbjf2b🧬 Is aging just wear-and-tear, or is it a built-in flaw in our biological “software”? Dr. João Pedro de Magalhães proposes an interesting perspective: our DNA is the hardware, while the epigenome acts as software. Over time, this “software” may become maladaptive, driving the aging Read more 🧵👇28 Feb 2026 20:00 +0000at://did:plc:zi7xsjosic4o7kbk53aen4sv/app.bsky.feed.post/3mfwzahdbjf2bhttps://bsky.app/profile/healthspanmed.bsky.social/post/3mfre74djtk2dNot all whey proteins are identical. Alpha-lactalbumin combines leucine for muscle with tryptophan for serotonin and melatonin pathways. New Research Review ↓ https://www.gethealthspan.com/research/article/alpha-lactalbumin-research https://gethealthspan.com/undefined/research/article/alpha-lactalbumin-research26 Feb 2026 14:00 +0000at://did:plc:zi7xsjosic4o7kbk53aen4sv/app.bsky.feed.post/3mfre74djtk2dhttps://bsky.app/profile/healthspanmed.bsky.social/post/3mfdgblycxz2rNew Research Review: SGLT2 Inhibitors as Metabolic Senolytics: Clearing Senescent Cells to Combat Pathological Aging https://gethealthspan.com/science/article/sglt2-inhibitors-metabolic-senolytics21 Feb 2026 01:00 +0000at://did:plc:zi7xsjosic4o7kbk53aen4sv/app.bsky.feed.post/3mfdgblycxz2rhttps://bsky.app/profile/healthspanmed.bsky.social/post/3mfavsmr2vy22SGLT2 inhibitors are known for glucose control. But a new study examined them through the hallmarks of aging—looking at telomeres, immune function, and metabolic stress. Our latest Research Review explores what this early evidence suggests ↓ https://www.gethealthspan.com/research/article/sglt2-inhibitors-longevity-markers https://gethealthspan.com/undefined/research/article/sglt2-inhibitors-longevity-markers20 Feb 2026 01:00 +0000at://did:plc:zi7xsjosic4o7kbk53aen4sv/app.bsky.feed.post/3mfavsmr2vy22https://bsky.app/profile/healthspanmed.bsky.social/post/3mf3e4f5zhf2iHair loss is usually framed as hormonal. But new research suggests it may also reflect aging biology inside the follicle—stem cell exhaustion, senescence, and impaired autophagy. Our latest Research Review explores the evidence ↓ https://www.gethealthspan.com/research/article/rapamycin-for-hair-loss-research https://gethealthspan.com/undefined/research/article/rapamycin-for-hair-loss-research17 Feb 2026 20:00 +0000at://did:plc:zi7xsjosic4o7kbk53aen4sv/app.bsky.feed.post/3mf3e4f5zhf2ihttps://bsky.app/profile/healthspanmed.bsky.social/post/3mesr6p5mse24What if the key to rapamycin and aging isn’t how much, but how often? New human data are reshaping how scientists think about dosing, timing, and the biology of cellular maintenance. Our latest Research Review dives into the evidence. https://www.gethealthspan.com/research/article/rapamycin-dosing-for-longevity https://gethealthspan.com/undefined/research/article/rapamycin-dosing-for-longevity14 Feb 2026 10:00 +0000at://did:plc:zi7xsjosic4o7kbk53aen4sv/app.bsky.feed.post/3mesr6p5mse24https://bsky.app/profile/healthspanmed.bsky.social/post/3mercaqj4z524Protein isn’t just about muscle. Amino acid composition influences sleep, circadian timing, metabolism, and brain chemistry. Our latest Research Review explores why not all whey proteins function identically—and what alpha-lactalbumin may reveal ↓ https://www.gethealthspan.com/research/article/alpha-lactalbumin-research https://gethealthspan.com/undefined/research/article/alpha-lactalbumin-research13 Feb 2026 20:00 +0000at://did:plc:zi7xsjosic4o7kbk53aen4sv/app.bsky.feed.post/3mercaqj4z524https://bsky.app/profile/healthspanmed.bsky.social/post/3mems3bg2tk2dSGLT2 inhibitors are known for glucose control. But a new study examined them through the hallmarks of aging—looking at telomeres, immune function, and metabolic stress. Our latest Research Review explores what this early evidence suggests ↓ https://www.gethealthspan.com/research/article/sglt2-inhibitors-longevity-markers https://gethealthspan.com/undefined/research/article/sglt2-inhibitors-longevity-markers12 Feb 2026 01:00 +0000at://did:plc:zi7xsjosic4o7kbk53aen4sv/app.bsky.feed.post/3mems3bg2tk2dhttps://bsky.app/profile/healthspanmed.bsky.social/post/3meg3it7dvo2pExercise is biological remodeling. The question is: what systems are being remodeled—and for how long? Our latest Research Review explores mitochondrial and vascular adaptation through an aging lens. Read → https://www.gethealthspan.com/research/article/exercise-modalities-and-mitochondrial-and-vascular-remodeling https://gethealthspan.com/undefined/research/article/exercise-modalities-and-mitochondrial-and-vascular-remodeling09 Feb 2026 09:00 +0000at://did:plc:zi7xsjosic4o7kbk53aen4sv/app.bsky.feed.post/3meg3it7dvo2phttps://bsky.app/profile/healthspanmed.bsky.social/post/3mecq7kcojy2dThe latest research reveals mitochondrial breakdown as a root driver of aging. We created a framework to track their health, diagnose decline, and apply interventions that protect lifespan. https://www.youtube.com/watch?v=QpWZheUD1_Y08 Feb 2026 01:00 +0000at://did:plc:zi7xsjosic4o7kbk53aen4sv/app.bsky.feed.post/3mecq7kcojy2dhttps://bsky.app/profile/healthspanmed.bsky.social/post/3meb5wcdpca2s1. 🧠 What if Alzheimer’s isn’t caused by plaques at all—but by an energy crisis inside your brain cells? The research of Dr. Francisco Gonzalez-Lima on mitochondrial dysfunction in AD—and the potential of methylene blue to restore neuronal energy—you see a radically different framing of the disease07 Feb 2026 10:00 +0000at://did:plc:zi7xsjosic4o7kbk53aen4sv/app.bsky.feed.post/3meb5wcdpca2shttps://bsky.app/profile/healthspanmed.bsky.social/post/3me5pbrc2im2mThe latest research reveals mitochondrial breakdown as a root driver of aging. We created a framework to track their health, diagnose decline, and apply interventions that protect lifespan. https://www.youtube.com/watch?v=QpWZheUD1_Y06 Feb 2026 01:00 +0000at://did:plc:zi7xsjosic4o7kbk53aen4sv/app.bsky.feed.post/3me5pbrc2im2mhttps://bsky.app/profile/healthspanmed.bsky.social/post/3me4kfr6okt2u🧬 Is aging just wear-and-tear, or is it a built-in flaw in our biological “software”? Dr. João Pedro de Magalhães proposes an interesting perspective: our DNA is the hardware, while the epigenome acts as software. Over time, this “software” may become maladaptive, driving the aging Read more 🧵👇05 Feb 2026 14:00 +0000at://did:plc:zi7xsjosic4o7kbk53aen4sv/app.bsky.feed.post/3me4kfr6okt2uhttps://bsky.app/profile/healthspanmed.bsky.social/post/3mdpknrr2wi2oThe latest research reveals mitochondrial breakdown as a root driver of aging. We created a framework to track their health, diagnose decline, and apply interventions that protect lifespan. https://www.youtube.com/watch?v=QpWZheUD1_Y31 Jan 2026 10:00 +0000at://did:plc:zi7xsjosic4o7kbk53aen4sv/app.bsky.feed.post/3mdpknrr2wi2ohttps://bsky.app/profile/healthspanmed.bsky.social/post/3mdjlkhr5ee2jNew Research Review: SGLT2 Inhibitors as Metabolic Senolytics: Clearing Senescent Cells to Combat Pathological Aging https://gethealthspan.com/science/article/sglt2-inhibitors-metabolic-senolytics29 Jan 2026 01:00 +0000at://did:plc:zi7xsjosic4o7kbk53aen4sv/app.bsky.feed.post/3mdjlkhr5ee2jhttps://bsky.app/profile/healthspanmed.bsky.social/post/3mdi4meblnb2c🧠 Is Alzheimer’s really a disease of misfolded proteins—or a crisis of cellular energy? For decades, the dominant theory of Alzheimer’s disease has focused on the growth of amyloid plaques. But a growing body of research points to a different culprit that may come earlier: mitochondrial dysfunction28 Jan 2026 11:00 +0000at://did:plc:zi7xsjosic4o7kbk53aen4sv/app.bsky.feed.post/3mdi4meblnb2c