Pediatric Hematologist/Oncologist, Geneticist, Stem Cell Biologist bloodgenes.orghttps://bsky.app/profile/bloodgenes.bsky.socialhttps://bsky.app/profile/bloodgenes.bsky.social/post/3mwreljuvfk2h🩸🧬 Delighted to share our new @nature.com paper! Genetic studies of >28,000 people reveal a BACH2-NRF2 pathway for activating fetal hemoglobin, suggesting new tx avenues for sickle cell disease & β-thalassemia. Led by the amazing Chun-Jie Guo & co! https://www.nature.com/articles/s41586-026-11113-230 Sep 2026 22:15 +0000at://did:plc:zvwp64j7pnsobppoiar7njkv/app.bsky.feed.post/3mwreljuvfk2hhttps://bsky.app/profile/bloodgenes.bsky.social/post/3msis5rj4r22d🚨Two complementary preprints from our group reveal convergent mechanisms of inherited B-ALL predisposition. Check out this terrific work led by @larawahlster.bsky.social, @alneehus.bsky.social & #AndrewLee! https://www.biorxiv.org/content/10.64898/2026.08.06.743305v1 https://www.biorxiv.org/content/10.64898/2026.08.06.743308v107 Aug 2026 14:43 +0000at://did:plc:zvwp64j7pnsobppoiar7njkv/app.bsky.feed.post/3msis5rj4r22dhttps://bsky.app/profile/bloodgenes.bsky.social/post/3msgpysoqg22y🚨👇 Check out this wonderful collaborative work identifying a new 3D genome regulator - Matchmakers - with the incredible @andersshansen.bsky.social ! Fantastic work led by Varshini Ramanathan and Chun-Jie Guo! [contains quote post or other embedded content]06 Aug 2026 18:59 +0000at://did:plc:zvwp64j7pnsobppoiar7njkv/app.bsky.feed.post/3msgpysoqg22yhttps://bsky.app/profile/bloodgenes.bsky.social/post/3mp4j4yd3x22r🙏 Deeply honored to receive the 2026 Warren Alpert Prize! This award reflects the work by so many to enable transformative therapies for sickle cell disease and thalassemia, and the power of human genetics to reveal biology and guide new treatments! https://hms.harvard.edu/news/2026-warren-alpert-foundation-prize-awarded-gene-editing-therapies25 Jun 2026 13:14 +0000at://did:plc:zvwp64j7pnsobppoiar7njkv/app.bsky.feed.post/3mp4j4yd3x22rhttps://bsky.app/profile/bloodgenes.bsky.social/post/3mnd6letpbk2v🩸🧬 Dendritic cells are rare but key players in immunity. In a new preprint led by @ofircohn.bsky.social, we generate a single-cell multi-omic atlas of human dendritic cell differentiation to reveal links to immune-mediated disease: https://www.biorxiv.org/content/10.64898/2026.05.28.728586v102 Jun 2026 18:03 +0000at://did:plc:zvwp64j7pnsobppoiar7njkv/app.bsky.feed.post/3mnd6letpbk2vhttps://bsky.app/profile/bloodgenes.bsky.social/post/3mmrl4unfcc2oI had such a wonderful time joining @stemcellpodcast for this conversation! It was a real pleasure to discuss how human genetics can illuminate 🩸 stem cell biology, hematopoiesis, and opportunities to develop better therapies. Thanks so much for having me! [contains quote post or other embedded content]26 May 2026 18:00 +0000at://did:plc:zvwp64j7pnsobppoiar7njkv/app.bsky.feed.post/3mmrl4unfcc2ohttps://bsky.app/profile/bloodgenes.bsky.social/post/3mlwbo7dw322lWonderful to spend time hiking with our incredible team! Grateful for this remarkable group and inspired every day by their creativity, dedication, kindness, and teamwork - both in and outside the lab. 🩸🧬15 May 2026 21:29 +0000at://did:plc:zvwp64j7pnsobppoiar7njkv/app.bsky.feed.post/3mlwbo7dw322lhttps://bsky.app/profile/bloodgenes.bsky.social/post/3mkv4vte6lk24🙏 🙏 Really honored to receive the Oski Memorial Award and be able to participate in #ASPHO2026!! Thank you, @aspho-hq.bsky.social! [contains quote post or other embedded content]02 May 2026 17:06 +0000at://did:plc:zvwp64j7pnsobppoiar7njkv/app.bsky.feed.post/3mkv4vte6lk24https://bsky.app/profile/bloodgenes.bsky.social/post/3mkst2yscoc2x🚨 Excited to share a new paper in Cell! Human genetics led us to HOTSCRAMBL, a HOXA-locus lncRNA that regulates 🩸#stemcell self-renewal and HOXA9 splicing, with implications for AML. Amazing work by @lvchosen1.bsky.social with many others! https://www.cell.com/cell/fulltext/S0092-8674(26)00439-301 May 2026 19:05 +0000at://did:plc:zvwp64j7pnsobppoiar7njkv/app.bsky.feed.post/3mkst2yscoc2xhttps://bsky.app/profile/bloodgenes.bsky.social/post/3mifhf46lgc2bhttps://www.fondazionetelethon.it/en/stories-and-news/news/from-telethon-foundation/in-memory-of-claudio-bordignon-pioneer-of-gene-therapy/01 Apr 2026 00:40 +0000at://did:plc:zvwp64j7pnsobppoiar7njkv/app.bsky.feed.post/3mifhf46lgc2b