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Dr Martha Gulati
drmarthagulati.bsky.social
did:plc:wo5qahyb3qa2qekcxaflkdq3
Dr. Nissen presents #ALPACA assessing siRNA in ⬇️ Lp(a) Lepodisiran
♥️400 mg dose: 95% ⬇️, sustained 180 days but still effects after at 540 days
♥️ Large ⬇️ in Lp(a)
♥️ ApoB ⬇️ by 15%
♥️ safety favorable: 1 withdrew in placebo
#ACC25 #CVPrev
@nejm.org
📎 https://www.nejm.org/doi/full/10.1056/NEJMoa2415818?utm_source=conf&utm_medium=qr&utm_campaign=ACC2025
2025-03-30T23:35:43.805Z