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Edward Nirenberg
enirenberg.bsky.social
did:plc:fpwat6yypl7sjbke3orwth7f
To program a T cell to be a regulatory T cell requires the action of a transcription factor (a protein that turns genes on or off) called FoxP3. In 2001, Mary Brunkow and Fred Ramsdell identified that IPEX syndrome was caused by mutations in FoxP3:
rdcu.be/eJHEr
https://rdcu.be/eJHEr
2025-10-06T13:04:56.186Z