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Fluicell
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Fast inactivation is an essential part of voltage gated sodium channel function, and its disruption is linked to multiple diseases. Clairfeuille et al. use a scorpion toxin that impedes fast inactivation to gain structural insights into the inactivation process and toxin pharmacology.
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https://doi.org/10.1126/science.aav8573
2024-12-13T13:05:29.051Z