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Andrew Deans
genomestability.bsky.social
did:plc:ooucgpiyqb6e6prmnp7tapr6
🧬 New from crystal structures from our lab in EMBO Journal! We reveal how the FANCM enzyme, an emerging therapeutic target it cancer, has evolved to specifically recognise branched DNA and activate the Fanconi anaemia pathway of DNA repair. https://doi.org/10.1038/s44318-025-00468-3 🧵👇
2025-06-02T00:42:19.152Z