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HillerLab
hillerlab.bsky.social
did:plc:ktlu5exmle3jpv77qygimups
PDIA6 condensates recruit Hsp70 BiP, ERdj3, and Grp94 creating a functional hub for protein folding. The condensates dissolve upon ER stress but reform after stress relief, regulated by Ca²⁺ levels. This dynamic switch suggests a novel mechanism for maintaining ER homeostasis!
2025-08-11T09:10:20.337Z