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Bloom lab
jbloomlab.bsky.social
did:plc:m4d6u5orqxgoxhbyeptrvn44
In new study led by @timyu.bsky.social, we measure how mutations to H3 flu HA affect cell entry, stability & antibody escape
We find pleiotropic effects of mutations on these phenotypes shape evolution: epistasis alleviates cell-entry but not stability constraints
https://www.biorxiv.org/content/10.1101/2025.05.24.655919v1
2025-05-27T16:23:14.744Z