This is a heavily interactive web application, and JavaScript is required. Simple HTML interfaces are possible, but that is not what this is.
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Jeff Spence
jeffspence.github.io
did:plc:mbx6k46ddyofdsqip5723wir
Excited to see @jonj-udd.bsky.social's fantastic work out @genetics-gsa.bsky.social.
Selection in _heterozygotes_ is the primary force shaping allele frequencies of loss-of-function mutations in humans, even in genes only associated with purely recessive diseases. 🧪🧬
https://doi.org/10.1093/genetics/iyag150
2026-06-22T19:11:15.961Z