@jimzphd.bsky.social on Bluesky

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Jim Zoladek

jimzphd.bsky.social

did:plc:5pql7zt66jxtl5p3w5jywawf

𝗛𝗼𝘄 𝗱𝗼𝗲𝘀 𝗠𝗜𝗧𝗗𝟭 𝗯𝗹𝗼𝗰𝗸 𝘃𝗶𝗿𝗮𝗹 𝗿𝗲𝗽𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻? 🧬 MITD1 overexpression forms cytoplasmic aggregates that deplete CHMP1B+4B, key ESCRT-III proteins. 🔬 PLA confirmed their recruitment to flavivirus replication factories. Knockdown of CHMP1B+4B hinders MITD1’s antiviral effect—proving a link

2025-03-20T20:40:25.782Z