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Matthew Taliaferro
jmtali.bsky.social
did:plc:3gudhdjwcbbs22mx7mvc4xnj
If we replace wildtype TDP-43 with an ALS mutant TDP-43, we again see that the same RNAs become aberrantly neurite-enriched. So this could be happening in ALS patient cells, but whether it makes contributions to patient phenotypes is another question for another day.
2025-03-03T16:00:29.860Z