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Jon Brudvig
jonbrudvig.bsky.social
did:plc:w4jum6mbgo7boqwefx5oaxm3
We’ve known for a while now that metformin doesn’t act primarily in the liver or mitochondria as was once believed. Instead, it concentrates in the gut, where it activates a cellular stress response.
Now, two new studies show exactly how this local response ripples outward to benefit metabolism. 🧪
2025-07-29T13:57:29.125Z