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IMAGE Lab
labphan.bsky.social
did:plc:koebhwgxnlh3iaiqybcqksa3
Cells exist in discrete cell states (clusters) but also cells show a continuum of gene expression (trajectory). @urialonlab.bsky.social first used archetype analysis to reconcile this paradox - the bioinformatic equivalent of wave-particle duality. This works if the ambient data space is linear. 2/3
https://www.sciencedirect.com/science/article/pii/S2405471218304824
2025-06-26T11:38:34.963Z