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María Mariner
mariamafau.bsky.social
did:plc:3wvtzgkojqhlwmfrlhziio4s
🎭 Act I: The Pioneer
At day 3 of differentiation (primed pluripotency), ZIC2 binds previously closed chromatin regions.
It opens them up — broadly “priming” putative regulatory elements, some linked to key neurodevelopmental genes.
📖A textbook case of pioneer transcription factor behavior.
2025-07-24T16:28:37.960Z