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Nikhil Milind
nikhilmilind.dev
did:plc:3jdl7ctmizdt3hs746kx3zi3
How well does TWAS estimate a gene’s direction of effect on a trait? We think of this as an important stress-test for the accuracy of TWAS.
In a new pre-print, we find that TWAS gets the sign wrong around 20-30% of the time!
https://doi.org/10.64898/2025.12.19.695550
1/n
2026-01-06T02:30:46.435Z