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Ryan Hisner
ryanhisner.bsky.social
did:plc:rcxyibhzcrkyqwjow4yddom6
After nearly 3 years of intrahost evolution in a chronically infected person, the new BA.3 is almost unrecognizable. It has ~41 spike AA substitutions (4 of which are 2-nucleotide mutations) to go with 14 AA deletions (∆136-147+∆243-244). We’ve seen nothing like this since 2023.
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2025-03-12T10:46:38.699Z