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Sasha Gusev
sashagusevposts.bsky.social
did:plc:glxbrjn4eltngwji5zi4fn33
The same phenomena holds for genome-wide epistasis between many loci. As the causal variants become more common, the epistasis (A*B) can be better approximated with additivity (A+B). For uniformly selected frequencies, >80% of biological epistasis looks like additivity!
2025-08-27T20:41:09.154Z