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Sasha Gusev
sashagusevposts.bsky.social
did:plc:glxbrjn4eltngwji5zi4fn33
There is no statistical power to identify individual rare var interactions. But interactions between rare variants and common polygenic scores can be tested and show ... nothing. This is genuinely surprising: large deleterious effects simply add up with common polygenic burden.
2025-08-27T20:41:09.312Z