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Ken Milne MD
thesgem.bsky.social
did:plc:evcoxxgf4clenv64hvmssqzo
89% got the correct answer. Less than 25% of single-centre RCTs of critically ill patients claiming a mortality benefit were replicated in a multi-centre RCT, the actual number being 6%.
https://thesgem.com/2025/01/sgem465-not-a-second-time-single-center-rcts-fail-to-replicate-in-multi-center-rcts/ @emcrit.bsky.social @kirstychallen.bsky.social
2025-01-15T01:05:20.056Z